Id |
Subject |
Object |
Predicate |
Lexical cue |
T606 |
0-82 |
Sentence |
denotes |
On the other hand, quercetin is a natural penta-hydroxylated flavonoid (Figure 9). |
T607 |
83-207 |
Sentence |
denotes |
Similar to resveratrol, quercetin possesses antioxidant, oxygen scavenging, anti-inflammatory, and cardioprotective effects. |
T608 |
208-326 |
Sentence |
denotes |
Quercetin also inhibits platelet aggregation and lipid peroxidation and affects the function of several kinases [282]. |
T609 |
327-427 |
Sentence |
denotes |
Importantly, quercetin also exhibits a wide spectrum antiviral activity against DNA and RNA viruses. |
T610 |
428-507 |
Sentence |
denotes |
For example, quercetin inhibited several respiratory viruses in cultured cells. |
T611 |
508-628 |
Sentence |
denotes |
It also inhibited the cytopathic effects of rhinoviruses, echoviruses, coxsackieviruses, and polioviruses [283,284,285]. |
T612 |
629-782 |
Sentence |
denotes |
Quercetin also significantly reduced plaque formation by polio virus, herpes simplex virus 1, respiratory syncytial virus, and parainfluenza virus [286]. |
T613 |
783-876 |
Sentence |
denotes |
Furthermore, quercetin inhibited the replication of cytomegalovirus and dengue virus 2 [287]. |
T614 |
877-1044 |
Sentence |
denotes |
The antiviral effects of quercetin are thought to be because it either blocks the virus entry or inhibits the viral replication enzymes, i.e., viral polymerases [288]. |
T615 |
1045-1128 |
Sentence |
denotes |
Other flavonoids have recently been reported as potential inhibitors of Mpro [289]. |
T616 |
1129-1263 |
Sentence |
denotes |
Accordingly, the effect of quercetin alone as a prophylactic or as a treatment is being tested in COVID-19 patients (NCT04377789; 50). |
T617 |
1264-1346 |
Sentence |
denotes |
It is also being tested with zinc, bromelain, and vitamin C (NCT04468139; n = 60). |