| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T705 |
0-4 |
Sentence |
denotes |
4.3. |
| T706 |
5-34 |
Sentence |
denotes |
Reporter-Detected In-Cell NMR |
| T707 |
35-150 |
Sentence |
denotes |
In-cell NMR extends beyond proteins, and has been applied successfully to DNA [93,421] and RNA molecules [422,423]. |
| T708 |
151-232 |
Sentence |
denotes |
Telomeric repeats have also been studied using target detected in-cell NMR [424]. |
| T709 |
233-422 |
Sentence |
denotes |
The reporter-detected in-cell NMR technique isotopically labels neither the ligand nor the target, but rather a receptor that indirectly measures the effects of ligand-target binding [409]. |
| T710 |
423-483 |
Sentence |
denotes |
The “reporter” varies according to the experimental context. |
| T711 |
484-635 |
Sentence |
denotes |
For instance, Dose et al. [425] used acetylation- and deacetylation-based assays to monitor the activity of histone deacetylase and acetyl-transferase. |
| T712 |
636-758 |
Sentence |
denotes |
Thongwichian et al. [426] used peptide-based reporters to identify active kinases and phosphatases in cellular conditions. |
| T713 |
759-924 |
Sentence |
denotes |
Lastly, Doura et al. [427] designed a 19F probe that operates in biological conditions in order to study the adherence and dynamics of proteins found in human blood. |
