| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T58 |
0-120 |
Sentence |
denotes |
The ACE2 gene codifies for a typical zinc-metallopeptidase of 805 amino acids (120 kDa), with a unique catalytic domain. |
| T59 |
121-231 |
Sentence |
denotes |
Despite the high resemblance of ACE and ACE2, considerable differences exist in their substrates and products. |
| T60 |
232-321 |
Sentence |
denotes |
While ACE acts as dipeptidase, ACE2 removes only a single amino acid from its substrates. |
| T61 |
322-573 |
Sentence |
denotes |
Therefore, ACE2 is not active in transforming angiotensin I to angiotensin II and in inactivating bradykinin; moreover, ACE2 is insensitive to ACE inhibitors, like lisinopril and captopril (Tipnis et al., 2000; Rice et al., 2004; Turner et al., 2004). |
