| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T437 |
0-83 |
Sentence |
denotes |
There is also increasing evidence that the RAAS system may be implicated in cancer. |
| T438 |
84-284 |
Sentence |
denotes |
ACE2 was found to inhibit cancer cell growth, metastasis, and angiogenesis in breast (Yu et al., 2016; Zhang Q. et al., 2019), pancreatic (Zhou et al., 2011), and colon cancer (Bernardi et al., 2012). |
| T439 |
285-494 |
Sentence |
denotes |
Another study pointed out that hepatocellular carcinoma patients with higher levels of ACE2 had longer survival times, suggesting a positive link between ACE2 expression and better prognosis (Ye et al., 2015). |
| T440 |
495-661 |
Sentence |
denotes |
Studies on human xenografts in mice clearly indicated that ACE2 inhibited tumor growth by suppressing invasion and angiogenesis in Non-Small Cell Lung Cancer (NSCLC). |
| T441 |
662-935 |
Sentence |
denotes |
Remarkably, the same group demonstrated that overexpression of ACE2 promotes the expression of E-cadherin at expenses of mesenchymal markers such as vimentin, and thereby inhibits the epithelial-mesenchymal transition in NSCLC models (Feng et al., 2010; Qian et al., 2013). |
