| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T336 |
0-240 |
Sentence |
denotes |
Epidemiological data consistently show that the COVID-19 patients at highest risk of a poor prognosis are males older than 60 years with chronic underlying diseases, mostly hypertension, cardiovascular diseases and type-2 diabetes mellitus. |
| T337 |
241-423 |
Sentence |
denotes |
Clinical reports have been rapidly delivered from all over the world, and meta-analyses assessing the prevalence of comorbidities and their impact on prognosis are already available. |
| T338 |
424-671 |
Sentence |
denotes |
A meta-analysis pooling data from seven studies following a total number of 1,576 infected patients from hospitals in China found that the most prevalent comorbidities were hypertension (21.1%), diabetes (9.7%), and cardiovascular diseases (8.4%). |
| T339 |
672-880 |
Sentence |
denotes |
These increased the risk of developing a more serious disease (i.e., requiring intensive care treatment), with odds ratios ranging from 2.4 (hypertension) to 3.4 (cardiovascular disease) (Yang et al., 2020b). |
| T340 |
881-1156 |
Sentence |
denotes |
These findings have been confirmed in the analysis performed by the Chinese Center for Disease Control and Prevention in a huge sample of 72314 COVID-19 cases (Epidemiology Working Group for Ncip Epidemic Response and Chinese Center for Disease Control and Prevention, 2020). |
| T341 |
1157-1310 |
Sentence |
denotes |
A study with 1591 Italian patients, similarly, reported a significant association between hypertension and mortality in Intensive Care Unit (63 vs. 40%). |
| T342 |
1311-1455 |
Sentence |
denotes |
This series reported an even higher prevalence of hypertension (49%), diabetes (17%), and cardiovascular disease (21%) (Grasselli et al., 2020). |
| T343 |
1456-1644 |
Sentence |
denotes |
Diabetes has been reported to predict the occurrence of ARDS (HR = 1.44), acute kidney injury (HR = 3.01), septic shock (HR = 1.95), and all-cause mortality (HR = 1.70) (Zhu et al., 2020). |
| T344 |
1645-1803 |
Sentence |
denotes |
Notably, poor glycemic control was significantly associated with worse clinical outcomes, namely multi-organ injuries and higher mortality (Zhu et al., 2020). |
| T345 |
1804-1885 |
Sentence |
denotes |
Obesity has also emerged as an important factor in determining COVID-19 severity. |
| T346 |
1886-2154 |
Sentence |
denotes |
Indeed, obesity was more frequent in patients admitted to critical care for SARS-CoV-2 as compared to the general population; moreover, the BMI was positively related to the need for invasive mechanical ventilation and mortality (Drucker, 2020; Simonnet et al., 2020). |
