Id |
Subject |
Object |
Predicate |
Lexical cue |
T180 |
0-65 |
Sentence |
denotes |
Additional players contribute to ACE2-mediated cardio-protection. |
T181 |
66-260 |
Sentence |
denotes |
Another substrate of ACE2 carboxypeptidase activity is Angiotensin A (Ang-A), identified in 2008, which has a similar, although less potent, vasopressor effect as AngII (Jankowski et al., 2007). |
T182 |
261-404 |
Sentence |
denotes |
The product of the enzymatic reaction catalyzed by ACE2 is the peptide Ala-Ang (1–7) also known as alamandine (Lautner et al., 2013; Figure 3). |
T183 |
405-540 |
Sentence |
denotes |
Alamandine receptor is a Mas-related G-protein coupled receptor, known as MrgD, which is expressed in cardiomyocytes and blood vessels. |
T184 |
541-683 |
Sentence |
denotes |
MrgD knockout animals develop a severe cardiopathy and alamandine showed a cardioprotective effect in a model of sepsis (Santos et al., 2019). |