LitCovid-sentences  

PMC:7546122 / 9602-11652 JSONTXT 6 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T65 0-23 Sentence denotes Testing of Human Plasma
T66 24-174 Sentence denotes To evaluate the potential development of SARS-CoV-2 antibodies in the plasma donor community, samples of plasma pools of 6 donations each were tested.
T67 175-309 Sentence denotes The use of pools enabled testing of a high amount of plasma donations for SARS-CoV-2 nAbs with the biosafety level-3 functional assay.
T68 310-483 Sentence denotes As the mean SARS-CoV-2 µNT50 of plasma donations is rather high (approximately 1:230 [9]) even the nAbs of only 1 positive sample within a pool are detectable in this assay.
T69 484-768 Sentence denotes Testing a total of 560 plasma pools of 6 donations each, in total reflective of 3360 plasma donations, from week 13 (ie, last week of March) until week 28 (ie, first week of July) 2020 revealed that most of these pools had SARS-CoV-2 µNT titers below the limit of detection (Table 1).
T70 769-844 Sentence denotes The first pool with detectable nAbs to SARS-CoV-2 was collected in week 14.
T71 845-907 Sentence denotes Further positive pools were found in weeks 15, 16, 24, and 28.
T72 908-1120 Sentence denotes Up to 7% of the tested pools showed nAbs to SARS-CoV-2, which indicates that up to 1.17% of the plasma donors were positive for SARS-CoV-2 nAbs at a cumulative incidence of COVID-19 in Austria of 0.21% (Table 1).
T73 1121-1129 Sentence denotes Table 1.
T74 1131-1188 Sentence denotes SARS-CoV-2 Neutralizing Antibodies in Tested Plasma Pools
T75 1189-1201 Sentence denotes Week in 2020
T76 1202-1239 Sentence denotes Parameter 13 14 15 16 20 24 28
T77 1240-1295 Sentence denotes Plasma pools ≥LOD, % 0.0 1.3 1.3 6.3 0.0 5.0 7.0
T78 1296-1339 Sentence denotes µNT50 of plasma pool titers ≥LOD, 1:X n.a.
T79 1341-1371 Sentence denotes 37 5 6, 18, 26, 34, 87 n.a.
T80 1373-1410 Sentence denotes 7, 10, 20, 22 4, 7, 8, 9, 12, 18, 24
T81 1411-1470 Sentence denotes Number of plasma pools tested 40 80 80 80 100 80 100
T82 1471-1564 Sentence denotes SARS-CoV-2 nAb positive plasma donors in Austria, % 0.00 0.21 0.21 1.04 0.00 0.83 1.17
T83 1565-1651 Sentence denotes Cumulative COVID-19 incidence in Austria, %a 0.10 0.14 0.16 0.17 0.18 0.19 0.21
T84 1652-1920 Sentence denotes Abbreviations: µNT50, neutralization titer for 50% of the wells; COVID-19, coronavirus disease 2019; LOD, limit of detection; n.a., not applicable; nAb, neutralizing antibody; PCR, polymerase chain reaction; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.
T85 1921-2050 Sentence denotes aSARS-CoV-2 PCR-positive individuals per 100 000 population in Austria are described as cumulative COVID-19 incidence in percent.