Id |
Subject |
Object |
Predicate |
Lexical cue |
T87 |
0-148 |
Sentence |
denotes |
Our analysis of IVIG lots revealed high nAb titers to HCoV-229E (Figure 1B), which confirmed the presence of functionally intact nAbs in these lots. |
T88 |
149-356 |
Sentence |
denotes |
It is interesting to note that in IVIG lots produced from recovered plasma significantly higher titers to HCoV-229E were found compared to IVIG lots produced from source plasma, independent of plasma origin. |
T89 |
357-417 |
Sentence |
denotes |
Recovered plasma is usually obtained from older donors [11]. |
T90 |
418-550 |
Sentence |
denotes |
A trend towards increasing probability of HCoV-229E infections with age has been detected in the Scottish [3] and US [4] population. |
T91 |
551-698 |
Sentence |
denotes |
Furthermore, higher HCoV-229E–specific nAb titers were found in older study participants (60–85 years) compared to younger ones (21–40 years) [12]. |
T92 |
699-957 |
Sentence |
denotes |
Thus, a higher infection rate with HCoV-229E in older people and consequently the generation of neutralizing HCoV-229E–specific antibodies in the older plasma donors would explain the higher HCoV-229E titers found in IVIG lots produced from recovered plasma. |