PMC:7546122 / 11665-12622 JSONTXT 7 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T87 0-148 Sentence denotes Our analysis of IVIG lots revealed high nAb titers to HCoV-229E (Figure 1B), which confirmed the presence of functionally intact nAbs in these lots.
T88 149-356 Sentence denotes It is interesting to note that in IVIG lots produced from recovered plasma significantly higher titers to HCoV-229E were found compared to IVIG lots produced from source plasma, independent of plasma origin.
T89 357-417 Sentence denotes Recovered plasma is usually obtained from older donors [11].
T90 418-550 Sentence denotes A trend towards increasing probability of HCoV-229E infections with age has been detected in the Scottish [3] and US [4] population.
T91 551-698 Sentence denotes Furthermore, higher HCoV-229E–specific nAb titers were found in older study participants (60–85 years) compared to younger ones (21–40 years) [12].
T92 699-957 Sentence denotes Thus, a higher infection rate with HCoV-229E in older people and consequently the generation of neutralizing HCoV-229E–specific antibodies in the older plasma donors would explain the higher HCoV-229E titers found in IVIG lots produced from recovered plasma.