PMC:7543426 / 138-1508 JSONTXT 7 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function

Id Subject Object Predicate Lexical cue
T4 0-8 Sentence denotes Abstract
T5 10-20 Sentence denotes Background
T6 21-317 Sentence denotes Descriptions of the pathological features of coronavirus disease-2019 (COVID-19) caused by the novel zoonotic pathogen severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) emanate from tissue biopsies, case reports, and small postmortem studies restricted to the lung and specific organs.
T7 318-383 Sentence denotes Whole-body autopsy studies of COVID-19 patients have been sparse.
T8 385-392 Sentence denotes Methods
T9 393-681 Sentence denotes To further define the pathology caused by SARS-CoV-2 across all body organs, we performed autopsies on 22 patients with COVID-19 (18 with comorbidities and 4 without comorbidities) who died at the National Institute for Infectious Diseases Lazzaro Spallanzani-IRCCS Hospital, Rome, Italy.
T10 682-785 Sentence denotes Tissues from the lung, heart, liver, kidney, spleen, and bone marrow (but not the brain) were examined.
T11 786-853 Sentence denotes Only lung tissues were subject to transmission electron microscopy.
T12 855-862 Sentence denotes Results
T13 863-901 Sentence denotes COVID-19 caused multisystem pathology.
T14 902-979 Sentence denotes Pulmonary and cardiovascular involvement were dominant pathological features.
T15 980-1133 Sentence denotes Extrapulmonary manifestations included hepatic, kidney, splenic, and bone marrow involvement, and microvascular injury and thrombosis were also detected.
T16 1134-1224 Sentence denotes These findings were similar in patients with or without preexisting medical comorbidities.
T17 1226-1237 Sentence denotes Conclusions
T18 1238-1370 Sentence denotes SARS-CoV-2 infection causes multisystem disease and significant pathology in most organs in patients with and without comorbidities.