PMC:7534795 / 22591-23218 JSONTXT 10 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T157 0-96 Sentence denotes • Ruxolitinib treatment for elevated cytokine levels and inflammatory response • Prospective RCT
T158 97-142 Sentence denotes • 18 to 75 years of age with severe infection
T159 143-192 Sentence denotes • Primary outcome of time to clinical improvement
T160 193-230 Sentence denotes • N = 20 ruxolitinib + standard care
T161 231-295 Sentence denotes • N = 21 placebo + standard care • Ruxolitinib 5 mg twice daily
T162 296-400 Sentence denotes • Placebo vitamin C 100 mg twice daily • No difference in primary endpoint HR 1.669 (95% CI 0.836–3.335)
T163 401-457 Sentence denotes • Improvement in lung computerized tomography (CT) scans
T164 458-627 Sentence denotes • Significantly reduced cytokine levels and CRP by day 3 • Ruxolitinib may hasten time of chest CT scan improvement and mitigate systemic inflammation (Cao et al., 2020)