| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T711 |
0-221 |
Sentence |
denotes |
An important aspect in considering n-3 PUFAs as adjunctive therapy in critically or severe ill patients is the time of intervention, duration of treatment, dose, composition of the preparation and route of administration. |
| T712 |
222-375 |
Sentence |
denotes |
The type and intensity of supportive treatment required by a patient is dependent upon the severity of disease and the possible need for hospitalization. |
| T713 |
376-542 |
Sentence |
denotes |
Existing literature demonstrates it may take weeks or months for standard doses of n-3 PUFAs to exert a biological effect due to a gradual replacement of membrane AA. |
| T714 |
543-732 |
Sentence |
denotes |
It has been hypothesized the acute supplementation with n-3 PUFAs may influence the inflammatory response in critically ill patients, particularly those with ALI (Martin & Stapleton, 2010). |
| T715 |
733-964 |
Sentence |
denotes |
For example, a randomized clinical trial showed daily enteral feeding of critically ill ALI patients with elevated levels EPA, DHA and gamma-linolenic acid significantly reduced lung inflammation and improved oxygenation by 4 days. |
| T716 |
965-1113 |
Sentence |
denotes |
This was associated with a decreased duration of mechanical ventilation, ICU length of stay and mortality (Gadek et al., 1999; Singer et al., 2006). |
| T717 |
1114-1524 |
Sentence |
denotes |
In a trial conducted by Pontes-Arruda et al. who studied patients with sepsis requiring mechanical ventilation, a diet enriched with EPA, gamma-linolenic acid and antioxidants delivered at a constant rate during a minimum of 4 days contributed to better ICU and hospital outcomes, oxygenation status, ventilator-free days and was associated with lower mortality at 28-day interval (Pontes-Arruda et al., 2006). |
