LitCovid-sentences  

PMC:7464116 / 66147-68825 JSONTXT 10 Projects

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Id Subject Object Predicate Lexical cue
T395 0-187 Sentence denotes However, kidney-transplant recipients appear to be at particularly high risk for critical COVID-19 illness because of both their chronic immunosuppression and coexisting conditions [130].
T396 188-495 Sentence denotes Recently, at Montefiore Medical Center, NY, 36 consecutive adult kidney-transplant recipients who were positive for COVID-19 were identified [131], and Columbia University Kidney transplant program enrolled 15 kidney transplant recipients who required hospitalization for confirmed COVID-19 infection [132].
T397 496-631 Sentence denotes Both reports described management, clinical course and outcomes of those patients living with a kidney transplant affected by COVID-19.
T398 632-697 Sentence denotes Patients were predominantly men, and the median age was 55 years.
T399 698-818 Sentence denotes The most common comorbidities were the following: hypertension, diabetes mellitus, history of smoking and heart disease.
T400 819-924 Sentence denotes Almost all patients were receiving tacrolimus, prednisone and mycophenolate mofetil or mycophenolic acid.
T401 925-1015 Sentence denotes The patients reported symptom onset ranging from 1 day to nearly 3 weeks before admission.
T402 1016-1115 Sentence denotes The most common initial symptom was fever, but also cough, dyspnea, malaise, diarrhea and myalgias.
T403 1116-1218 Sentence denotes Over 50% of the patients had bilateral/multifocal opacities noted on initial chest x-ray radiographic.
T404 1219-1308 Sentence denotes Laboratory findings were lymphopenia, thrombocytopenia, low CD3, CD4 and CD8 cell counts.
T405 1309-1408 Sentence denotes As inflammatory markers, ferritin levels, C- reactive protein, procalcitonin and D-dimer were high.
T406 1409-1507 Sentence denotes Patients who were in a stable condition without major respiratory symptoms were monitored at home.
T407 1508-1819 Sentence denotes In another report, among 41 outpatient kidney transplant recipients with suspected or known COVID-19 infection, about one third required hospitalization by the end of their follow-up; there were no differences in demographics or medical comorbidities between those who were or were not admitted to the hospital.
T408 1820-1950 Sentence denotes These patients therefore required close clinical monitoring to prevent their organ deterioration until symptoms’ resolution [133].
T409 1951-2210 Sentence denotes As reported by Montefiore Medical Center and Columbia University, almost half of the patients had AKI, although none had a kidney biopsy performed to determine the cause, and required intubation and mechanical ventilation between 0 and 9 days after admission.
T410 2211-2379 Sentence denotes In particular, Columbia University’s report observed that 27% of their cases required intubation, a proportion that is similar for cases in New York City overall [132].
T411 2380-2452 Sentence denotes Among the patients who developed AKI, only 20% of patients required RRT.
T412 2453-2566 Sentence denotes At a median follow-up of 21 days, the mortality rate was about 28% of the kidney-transplant recipients [131,132].
T413 2567-2678 Sentence denotes Patients were managed with immunosuppression reduction and the addition of hydroxychloroquine and azithromycin.