Id |
Subject |
Object |
Predicate |
Lexical cue |
T193 |
0-118 |
Sentence |
denotes |
The genetic code of SARS‐CoV‐2 shares noticeable similarities with SARS‐CoV‐1, which caused the SARS epidemic in 2002. |
T194 |
119-199 |
Sentence |
denotes |
26 , 54 More importantly, both viruses have identical mechanisms of infection. |
T195 |
200-382 |
Sentence |
denotes |
SARS‐CoV‐1 uses the host's ACE2 as a portal to infect cells, which has high expression in the vascular endothelium 55 and the lung, particularly in type 2 alveolar epithelial cells. |
T196 |
383-450 |
Sentence |
denotes |
56 SARS‐CoV‐2 shares 76% of its spike (S) protein with SARS‐CoV‐1. |
T197 |
451-685 |
Sentence |
denotes |
Despite a few amino acid differences in its RBD compared to the SARS‐CoV‐1 S protein, the SARS‐CoV‐2 S protein binds to ACE2 with even greater affinity 27 offering an explanation for its greater virulence and preference for the lung. |