| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T604 |
0-169 |
Sentence |
denotes |
The S protein plays a significant role in the induction of protective immunity against SARS-CoV by mediating T-cell responses and neutralizing antibody production (168). |
| T605 |
170-318 |
Sentence |
denotes |
In the past few decades, we have seen several attempts to develop a vaccine against human coronaviruses by using S protein as the target (168, 169). |
| T606 |
319-460 |
Sentence |
denotes |
However, the developed vaccines have minimal application, even among closely related strains of the virus, due to a lack of cross-protection. |
| T607 |
461-578 |
Sentence |
denotes |
That is mainly because of the extensive diversity existing among the different antigenic variants of the virus (104). |
| T608 |
579-844 |
Sentence |
denotes |
The contributions of the structural proteins, like spike (S), matrix (M), small envelope (E), and nucleocapsid (N) proteins, of SARS-CoV to induce protective immunity has been evaluated by expressing them in a recombinant parainfluenza virus type 3 vector (BHPIV3). |
| T609 |
845-1077 |
Sentence |
denotes |
Of note, the result was conclusive that the expression of M, E, or N proteins without the presence of S protein would not confer any noticeable protection, with the absence of detectable serum SARS-CoV-neutralizing antibodies (170). |
| T610 |
1078-1214 |
Sentence |
denotes |
Antigenic determinant sites present over S and N structural proteins of SARS-CoV-2 can be explored as suitable vaccine candidates (294). |
| T611 |
1215-1352 |
Sentence |
denotes |
In the Asian population, S, E, M, and N proteins of SARS-CoV-2 are being targeted for developing subunit vaccines against COVID-19 (295). |
