PMC:7405836 / 77002-79135 JSONTXT 8 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T545 0-70 Sentence denotes SARS-CoV-2 infection can also be confirmed by isolation and culturing.
T546 71-163 Sentence denotes The human airway epithelial cell culture was found to be useful in isolating SARS-CoV-2 (3).
T547 164-247 Sentence denotes The efficient control of an outbreak depends on the rapid diagnosis of the disease.
T548 248-441 Sentence denotes Recently, in response to the COVID-19 outbreak, 1-step quantitative real-time reverse transcription-PCR assays were developed that detect the ORF1b and N regions of the SARS-CoV-2 genome (156).
T549 442-508 Sentence denotes That assay was found to achieve the rapid detection of SARS-CoV-2.
T550 509-674 Sentence denotes Nucleic acid-based assays offer high accuracy in the diagnosis of SARS-CoV-2, but the current rate of spread limits its use due to the lack of diagnostic assay kits.
T551 675-800 Sentence denotes This will further result in the extensive transmission of COVID-19, since only a portion of suspected cases can be diagnosed.
T552 801-1006 Sentence denotes In such situations, conventional serological assays, like enzyme-linked immunosorbent assay (ELISA), that are specific to COVID-19 IgM and IgG antibodies can be used as a high-throughput alternative (149).
T553 1007-1100 Sentence denotes At present, there is no diagnostic kit available for detecting the SARS-CoV-2 antibody (150).
T554 1101-1312 Sentence denotes The specific antibody profiles of COVID-19 patients were analyzed, and it was found that the IgM level lasted more than 1 month, indicating a prolonged stage of virus replication in SARS-CoV-2-infected patients.
T555 1313-1391 Sentence denotes The IgG levels were found to increase only in the later stages of the disease.
T556 1392-1498 Sentence denotes These findings indicate that the specific antibody profiles of SARS-CoV-2 and SARS-CoV were similar (325).
T557 1499-1632 Sentence denotes These findings can be utilized for the development of specific diagnostic tests against COVID-19 and can be used for rapid screening.
T558 1633-1838 Sentence denotes Even though diagnostic test kits are already available that can detect the genetic sequences of SARS-CoV-2 (95), their availability is a concern, as the number of COVID-19 cases is skyrocketing (155, 157).
T559 1839-2012 Sentence denotes A major problem associated with this diagnostic kit is that it works only when the test subject has an active infection, limiting its use to the earlier stages of infection.
T560 2013-2133 Sentence denotes Several laboratories around the world are currently developing antibody-based diagnostic tests against SARS-CoV-2 (157).