PMC:7405836 / 74966-77001 JSONTXT 8 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T533 0-277 Sentence denotes A suspected case of COVID-19 infection is said to be confirmed if the respiratory tract aspirate or blood samples test positive for SARS-CoV-2 nucleic acid using RT-PCR or by the identification of SARS-CoV-2 genetic sequence in respiratory tract aspirate or blood samples (80).
T534 278-374 Sentence denotes The patient will be confirmed as cured when two subsequent oral swab results are negative (153).
T535 375-477 Sentence denotes Recently, the live virus was detected in the self-collected saliva of patients infected with COVID-19.
T536 478-624 Sentence denotes These findings were confirmative of using saliva as a noninvasive specimen for the diagnosis of COVID-19 infection in suspected individuals (152).
T537 625-815 Sentence denotes It has also been observed that the initial screening of COVID-19 patients infected with RT-PCR may give negative results even if they have chest CT findings that are suggestive of infection.
T538 816-1025 Sentence denotes Hence, for the accurate diagnosis of COVID-19, a combination of repeated swab tests using RT-PCR and CT scanning is required to prevent the possibility of false-negative results during disease screening (154).
T539 1026-1086 Sentence denotes RT-PCR is the most widely used test for diagnosing COVID-19.
T540 1087-1228 Sentence denotes However, it has some significant limitations from the clinical perspective, since it will not give any clarity regarding disease progression.
T541 1229-1360 Sentence denotes Droplet digital PCR (ddPCR) can be used for the quantification of viral load in the samples obtained from lower respiratory tracts.
T542 1361-1452 Sentence denotes Hence, based on the viral load, we can quickly evaluate the progression of infection (291).
T543 1453-1809 Sentence denotes In addition to all of the above findings, sequencing and phylogenetics are critical in the correct identification and confirmation of the causative viral agent and useful to establish relationships with previous isolates and sequences, as well as to know, especially during an epidemic, the nucleotide and amino acid mutations and the molecular divergence.
T544 1810-2035 Sentence denotes The rapid development and implementation of diagnostic tests against emerging novel diseases like COVID-19 pose significant challenges due to the lack of resources and logistical limitations associated with an outbreak (155).