Id |
Subject |
Object |
Predicate |
Lexical cue |
T131 |
0-45 |
Sentence |
denotes |
The N protein of coronavirus is multipurpose. |
T132 |
46-260 |
Sentence |
denotes |
Among several functions, it plays a role in complex formation with the viral genome, facilitates M protein interaction needed during virion assembly, and enhances the transcription efficiency of the virus (55, 56). |
T133 |
261-397 |
Sentence |
denotes |
It contains three highly conserved and distinct domains, namely, an NTD, an RNA-binding domain or a linker region (LKR), and a CTD (57). |
T134 |
398-545 |
Sentence |
denotes |
The NTD binds with the 3′ end of the viral genome, perhaps via electrostatic interactions, and is highly diverged both in length and sequence (58). |
T135 |
546-652 |
Sentence |
denotes |
The charged LKR is serine and arginine rich and is also known as the SR (serine and arginine) domain (59). |
T136 |
653-771 |
Sentence |
denotes |
The LKR is capable of direct interaction with in vitro RNA interaction and is responsible for cell signaling (60, 61). |
T137 |
772-900 |
Sentence |
denotes |
It also modulates the antiviral response of the host by working as an antagonist for interferon (IFN) and RNA interference (62). |
T138 |
901-1158 |
Sentence |
denotes |
Compared to that of SARS-CoV, the N protein of SARS-CoV-2 possess five amino acid mutations, where two are in the intrinsically dispersed region (IDR; positions 25 and 26), one each in the NTD (position 103), LKR (position 217), and CTD (position 334) (16). |