PMC:7405836 / 18490-19648 JSONTXT 8 Projects

Annnotations TAB TSV DIC JSON TextAE-old TextAE

Id Subject Object Predicate Lexical cue
T131 0-45 Sentence denotes The N protein of coronavirus is multipurpose.
T132 46-260 Sentence denotes Among several functions, it plays a role in complex formation with the viral genome, facilitates M protein interaction needed during virion assembly, and enhances the transcription efficiency of the virus (55, 56).
T133 261-397 Sentence denotes It contains three highly conserved and distinct domains, namely, an NTD, an RNA-binding domain or a linker region (LKR), and a CTD (57).
T134 398-545 Sentence denotes The NTD binds with the 3′ end of the viral genome, perhaps via electrostatic interactions, and is highly diverged both in length and sequence (58).
T135 546-652 Sentence denotes The charged LKR is serine and arginine rich and is also known as the SR (serine and arginine) domain (59).
T136 653-771 Sentence denotes The LKR is capable of direct interaction with in vitro RNA interaction and is responsible for cell signaling (60, 61).
T137 772-900 Sentence denotes It also modulates the antiviral response of the host by working as an antagonist for interferon (IFN) and RNA interference (62).
T138 901-1158 Sentence denotes Compared to that of SARS-CoV, the N protein of SARS-CoV-2 possess five amino acid mutations, where two are in the intrinsically dispersed region (IDR; positions 25 and 26), one each in the NTD (position 103), LKR (position 217), and CTD (position 334) (16).