PMC:7405836 / 13452-14197 JSONTXT 8 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T87 0-56 Sentence denotes Coronavirus genomes and subgenomes encode six ORFs (31).
T88 57-131 Sentence denotes The majority of the 5′ end is occupied by ORF1a/b, which produces 16 nsps.
T89 132-254 Sentence denotes The two polyproteins, pp1a and pp1ab, are initially produced from ORF1a/b by a −1 frameshift between ORF1a and ORF1b (32).
T90 255-423 Sentence denotes The virus-encoded proteases cleave polyproteins into individual nsps (main protease [Mpro], chymotrypsin-like protease [3CLpro], and papain-like proteases [PLPs]) (42).
T91 424-515 Sentence denotes SARS-CoV-2 also encodes these nsps, and their functions have been elucidated recently (31).
T92 516-745 Sentence denotes Remarkably, a difference between SARS-CoV-2 and other CoVs is the identification of a novel short putative protein within the ORF3 band, a secreted protein with an alpha helix and beta-sheet with six strands encoded by ORF8 (31).