PMC:7402624 / 46516-47610 JSONTXT 8 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T267 0-112 Sentence denotes We next investigated how the UMAP Components were associated with individual immune features (tables S5 and S6).
T268 113-249 Sentence denotes UMAP Component 1 captured immune features, including the relative loss of CD4 and CD8 T cells and increase in nonB:nonT cells (Fig. 6G).
T269 250-296 Sentence denotes PB also associated with Component 1 (Fig. 6G).
T270 297-385 Sentence denotes Other individual B cell features were differentially captured by UMAP Component 1 and 2.
T271 386-550 Sentence denotes Component 1 contained a signal for T-bet+ PB populations (table S5) whereas Component 2 was enriched for T-bet+ memory B cells and CD138+ PB populations (table S6).
T272 551-770 Sentence denotes Activated HLA-DR+CD38+ and KI67+ CD4 and CD8 T cells had contributions to both Component 1 and Component 2, with these features residing in the upper right corner of the UMAP plot (Fig. 6, G and H, and fig. S8, A to D).
T273 771-955 Sentence denotes In contrast, T-bet+ non-naïve CD8 T cells were strongly associated with Component 2 whereas T-bet+ non-naïve CD4 T cells were also linked to Component 1 (Fig. 6G and tables S5 and S6).
T274 956-1094 Sentence denotes Eomes+ CD8 or CD4 T cells were both associated with Component 2 and negatively associated with Component 1 (Fig. 6G and tables S5 and S6).