Id |
Subject |
Object |
Predicate |
Lexical cue |
T23 |
0-119 |
Sentence |
denotes |
Most patients seroconvert within 7-14 days of infection and increased plasmablasts (PB) have been reported (16, 21–23). |
T24 |
120-207 |
Sentence |
denotes |
However, the role of humoral responses in the pathogenesis of COVID-19 remains unclear. |
T25 |
208-358 |
Sentence |
denotes |
Whereas IgG levels reportedly drop slightly ~8 weeks after symptom onset (24, 25), recovered patients maintain high Spike-specific IgG titers (6, 26). |
T26 |
359-440 |
Sentence |
denotes |
IgA levels also can remain high and may correlate with disease severity (25, 27). |
T27 |
441-543 |
Sentence |
denotes |
Furthermore, neutralizing antibodies can control SARS-CoV2 infection in vitro and in vivo (4, 28, 29). |
T28 |
544-642 |
Sentence |
denotes |
Indeed, convalescent plasma containing neutralizing antibodies can improve clinical symptoms (30). |
T29 |
643-842 |
Sentence |
denotes |
However, not all patients that recover from COVID-19 have detectable neutralizing antibodies (6, 26), suggesting a complex relationship between humoral and cellular response in COVID-19 pathogenesis. |