PMC:7396557 / 94814-96372 JSONTXT 12 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T713 0-45 Sentence denotes Progress of Pharmacological Research on AGNHP
T714 46-190 Sentence denotes Modern pharmacological studies have shown that AGNHP has antipyretic, analgesic, anti-inflammatory, and neuroprotective effects (see Table 3 ).
T715 191-422 Sentence denotes Zuguang Ye et al. discovered that AGNHP could significantly reduce the body temperature of hyperpyrexic rabbits in a fever model induced by intravenous injection of typhoid Vi polysaccharide vaccine in rabbit ear (Ye et al., 2003).
T716 423-683 Sentence denotes Feng Zhang, Kunjie Zhu et al. found in an LPS-induced intracerebral inflammation model that AGNHP antagonized the toxic effect of LPS on dopaminergic neurons, inhibited release of superoxide radical, and reverse changes in cortical monoamine neurotransmitters.
T717 684-890 Sentence denotes It was speculated that its impact on cortical monoamine neurotransmitters might be one of the mechanisms by which AGNHP promoted consciousness in LPS brain damage (Zhang F. et al., 2010; Zhu and Sun, 2014).
T718 891-1040 Sentence denotes Research by Dan Zhang et al. showed that AGNHP lowered serum LPS and lung myeloperoxidase (MPO) levels in a rat model of sepsis (Zhang et al., 2009).
T719 1041-1250 Sentence denotes Yishan Tang et al. found that AGNHP lowered total LDH activity in serum and brain tissue, and changed the percentage of isomerase in a rat pertussis-induced infectious cerebral edema model (Tang et al., 2005).
T720 1251-1428 Sentence denotes Fan Q et al. discovered that AGNHP had anti-atherosclerotic effects in the high fat diet-induced ApoE−/− mouse model at early- and mid-stage via regulation of Th17/Treg balance.
T721 1429-1558 Sentence denotes It inhibited chronic inflammation, reduced plaque collagen fibers, and reduced inflammatory cell infiltration (Fan et al., 2020).