LitCovid-sentences  

PMC:7396557 / 87560-89806 JSONTXT 11 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T660 0-43 Sentence denotes Progress of Pharmacological Research on SMI
T661 44-234 Sentence denotes Modern pharmacological studies have shown that SMI has functions that include protection from inflammatory shock, protection of heart and lung function, and immunoregulation (see Table 3 ).
T662 235-237 Sentence denotes Y.
T663 238-240 Sentence denotes Z.
T664 241-443 Sentence denotes Zhang et al. observed that SMI had strong anti-shock and neuroprotective properties in LPS-induced shock, possibly due to inhibition of brain lipid peroxidation and improvement of SOD activity (Zhang Y.
T665 444-461 Sentence denotes Z. et al., 2010).
T666 462-723 Sentence denotes SMI suppressed apoptosis of lung tissue cells during pulmonary ischemia/reperfusion injury in rabbits, resulting in attenuation of pneumocyte injury by raising NO levels, lowering oxygen free radical levels, and decreasing lipid peroxidation (Lin et al., 2007).
T667 724-981 Sentence denotes It has also been reported that SMI reduced expression of NF-κB and activity of inducible nitric oxide synthase (iNOS) in lung tissues of rats poisoned by paraquat, and significantly alleviated erythrocyte diapedesis in the alveolar space (Liu et al., 2009).
T668 982-1122 Sentence denotes Research by Shuhua Xu et al. showed that SMI improved cardiac function and significantly improved hemodynamics in rats with cardiac failure.
T669 1123-1277 Sentence denotes In addition, it improved the oxygen supply to tissues and the capacity of the tissues to use oxygen, thus, improving oxygen metabolism (Xu and Liu, 2010).
T670 1278-1551 Sentence denotes SMI also inhibited expression of ICAM-1 and vascular cell adhesion molecule 1 (VCAM-1) to alleviate inflammatory infiltration following ischemia/reperfusion, and alleviated myocardial ischemia/reperfusion injury caused by multiple inflammatory responses (Liu et al., 2015).
T671 1552-1820 Sentence denotes It also inhibited generation of inflammatory cytokines in rats subjected to ischemia/reperfusion, reduced serum expression of TNF-α, IL-6, IL-8, etc., thus, alleviating inflammatory factor-induced cardiomyocyte injury and improving immune function (Wang et al., 2015).
T672 1821-2005 Sentence denotes Research by Xuan Liu et al. discovered that SMI inhibited MCP-1, which indicated that SMI might be important in the inhibition of monocyte and macrophage activation (Liu et al., 2015).
T673 2006-2246 Sentence denotes Lihua Du discovered that SMI significantly increased the weights of thymus and spleen in mice, raised serum IgG levels and the number of T cells, enhanced the phagocytic function of macrophages and had a significant immunomodulatory effect.