Id |
Subject |
Object |
Predicate |
Lexical cue |
T660 |
0-43 |
Sentence |
denotes |
Progress of Pharmacological Research on SMI |
T661 |
44-234 |
Sentence |
denotes |
Modern pharmacological studies have shown that SMI has functions that include protection from inflammatory shock, protection of heart and lung function, and immunoregulation (see Table 3 ). |
T662 |
235-237 |
Sentence |
denotes |
Y. |
T663 |
238-240 |
Sentence |
denotes |
Z. |
T664 |
241-443 |
Sentence |
denotes |
Zhang et al. observed that SMI had strong anti-shock and neuroprotective properties in LPS-induced shock, possibly due to inhibition of brain lipid peroxidation and improvement of SOD activity (Zhang Y. |
T665 |
444-461 |
Sentence |
denotes |
Z. et al., 2010). |
T666 |
462-723 |
Sentence |
denotes |
SMI suppressed apoptosis of lung tissue cells during pulmonary ischemia/reperfusion injury in rabbits, resulting in attenuation of pneumocyte injury by raising NO levels, lowering oxygen free radical levels, and decreasing lipid peroxidation (Lin et al., 2007). |
T667 |
724-981 |
Sentence |
denotes |
It has also been reported that SMI reduced expression of NF-κB and activity of inducible nitric oxide synthase (iNOS) in lung tissues of rats poisoned by paraquat, and significantly alleviated erythrocyte diapedesis in the alveolar space (Liu et al., 2009). |
T668 |
982-1122 |
Sentence |
denotes |
Research by Shuhua Xu et al. showed that SMI improved cardiac function and significantly improved hemodynamics in rats with cardiac failure. |
T669 |
1123-1277 |
Sentence |
denotes |
In addition, it improved the oxygen supply to tissues and the capacity of the tissues to use oxygen, thus, improving oxygen metabolism (Xu and Liu, 2010). |
T670 |
1278-1551 |
Sentence |
denotes |
SMI also inhibited expression of ICAM-1 and vascular cell adhesion molecule 1 (VCAM-1) to alleviate inflammatory infiltration following ischemia/reperfusion, and alleviated myocardial ischemia/reperfusion injury caused by multiple inflammatory responses (Liu et al., 2015). |
T671 |
1552-1820 |
Sentence |
denotes |
It also inhibited generation of inflammatory cytokines in rats subjected to ischemia/reperfusion, reduced serum expression of TNF-α, IL-6, IL-8, etc., thus, alleviating inflammatory factor-induced cardiomyocyte injury and improving immune function (Wang et al., 2015). |
T672 |
1821-2005 |
Sentence |
denotes |
Research by Xuan Liu et al. discovered that SMI inhibited MCP-1, which indicated that SMI might be important in the inhibition of monocyte and macrophage activation (Liu et al., 2015). |
T673 |
2006-2246 |
Sentence |
denotes |
Lihua Du discovered that SMI significantly increased the weights of thymus and spleen in mice, raised serum IgG levels and the number of T cells, enhanced the phagocytic function of macrophages and had a significant immunomodulatory effect. |