Id |
Subject |
Object |
Predicate |
Lexical cue |
T832 |
0-8 |
Sentence |
denotes |
Ai 2020a |
T833 |
9-30 |
Sentence |
denotes |
Study characteristics |
T834 |
31-465 |
Sentence |
denotes |
Patient Sampling Purpose: diagnosis of SARS‐CoV‐2 pneumoniaDesign: cross‐sectional multicentre prospective studyRecruitment: hospitalised pneumonia patientsSample size: n = 53 (20 cases)Inclusion criteria: suspected SARS‐COV‐2 pneumonia patients, defined as having pneumonia after chest CT (with 1 of the 2 following criteria met: fever or respiratory symptoms, normal or decreased WBC counts/decreasedExclusion criteria: not defined |
T835 |
466-778 |
Sentence |
denotes |
Patient characteristics and setting Facility cases: confirmed case: a positive SARS‐COV‐2 nucleotides result either by metagenomic sequencing or RT‐PCR assay for nasopharyngeal swab specimensFacility controls: pneumonia patients confirmed not to be infected by SARS‐Cov2 (2 PCR tests, 2 days in between)Country: |
T836 |
779-790 |
Sentence |
denotes |
ChinaDates: |
T837 |
791-1272 |
Sentence |
denotes |
22 January 2020‐19 February 2020Symptoms and severity: suspected SARS‐COV‐2 pneumonia (NCP): having pneumonia after chest CT with 1 of the 2 following criteria met: fever or respiratory symptoms, normal or decreased WBC counts/decreased lymphocyte counts, and a travel history or contact with patients with fever or respiratory symptoms from Hubei Province or confirmed cases within 2 weeksDemographics: median age cases 37 years, controls 39 years, gender distribution cases (M/F: |
T838 |
1273-1295 |
Sentence |
denotes |
50/50), controls (M/F: |
T839 |
1296-1337 |
Sentence |
denotes |
48.5/51.5)Exposure history: not specified |
T840 |
1338-1356 |
Sentence |
denotes |
Index tests Fever |
T841 |
1357-1366 |
Sentence |
denotes |
Dry cough |
T842 |
1367-1376 |
Sentence |
denotes |
Diarrhoea |
T843 |
1377-1384 |
Sentence |
denotes |
Fatigue |
T844 |
1385-1393 |
Sentence |
denotes |
Headache |
T845 |
1394-1402 |
Sentence |
denotes |
Vomiting |
T846 |
1403-1417 |
Sentence |
denotes |
Abdominal pain |
T847 |
1418-1484 |
Sentence |
denotes |
Target condition and reference standard(s) TC: COVID‐19 pneumonia |
T848 |
1485-1656 |
Sentence |
denotes |
RS: a positive SARS‐COV‐2 nucleotides result either by metagenomic sequencing or RT‐PCR assay for nasopharyngeal swab specimens, repeated after 2 days if negative on day 0 |
T849 |
1657-1702 |
Sentence |
denotes |
Flow and timing Time interval not specified. |
T850 |
1703-1815 |
Sentence |
denotes |
Reference standard at day 0 and day 2, index tests from electronic medical records but stated at pneumonia onset |
T851 |
1816-1830 |
Sentence |
denotes |
Comparative |
T852 |
1831-1839 |
Sentence |
denotes |
Notes |
T853 |
1840-1862 |
Sentence |
denotes |
Methodological quality |
T854 |
1863-1928 |
Sentence |
denotes |
Item Authors' judgement Risk of bias Applicability concerns |
T855 |
1929-1938 |
Sentence |
denotes |
DOMAIN 1: |
T856 |
1939-1956 |
Sentence |
denotes |
Patient Selection |
T857 |
1957-2013 |
Sentence |
denotes |
Was a consecutive or random sample of patients enrolled? |
T858 |
2015-2028 |
Sentence |
denotes |
Unclear |
T859 |
2029-2063 |
Sentence |
denotes |
Was a case‐control design avoided? |
T860 |
2065-2074 |
Sentence |
denotes |
Yes |
T861 |
2075-2120 |
Sentence |
denotes |
Did the study avoid inappropriate exclusions? |
T862 |
2122-2135 |
Sentence |
denotes |
Unclear |
T863 |
2136-2181 |
Sentence |
denotes |
Did the study avoid inappropriate inclusions? |
T864 |
2183-2191 |
Sentence |
denotes |
No |
T865 |
2192-2262 |
Sentence |
denotes |
Could the selection of patients have introduced bias? High risk |
T866 |
2263-2366 |
Sentence |
denotes |
Are there concerns that the included patients and setting do not match the review question? High |
T867 |
2367-2376 |
Sentence |
denotes |
DOMAIN 2: |
T868 |
2377-2399 |
Sentence |
denotes |
Index Test (All tests) |
T869 |
2400-2499 |
Sentence |
denotes |
Were the index test results interpreted without knowledge of the results of the reference standard? |
T870 |
2501-2514 |
Sentence |
denotes |
Unclear |
T871 |
2515-2561 |
Sentence |
denotes |
If a threshold was used, was it pre‐specified? |
T872 |
2563-2571 |
Sentence |
denotes |
No |
T873 |
2572-2664 |
Sentence |
denotes |
Could the conduct or interpretation of the index test have introduced bias? High risk |
T874 |
2665-2787 |
Sentence |
denotes |
Are there concerns that the index test, its conduct, or interpretation differ from the review question? Low concern |
T875 |
2788-2797 |
Sentence |
denotes |
DOMAIN 3: |
T876 |
2798-2816 |
Sentence |
denotes |
Reference Standard |
T877 |
2817-2894 |
Sentence |
denotes |
Is the reference standards likely to correctly classify the target condition? |
T878 |
2896-2905 |
Sentence |
denotes |
Yes |
T879 |
2906-3006 |
Sentence |
denotes |
Were the reference standard results interpreted without knowledge of the results of the index tests? |
T880 |
3008-3021 |
Sentence |
denotes |
Unclear |
T881 |
3022-3124 |
Sentence |
denotes |
Could the reference standard, its conduct, or its interpretation have introduced bias? Low risk |
T882 |
3125-3254 |
Sentence |
denotes |
Are there concerns that the target condition as defined by the reference standard does not match the question? Low concern |
T883 |
3255-3264 |
Sentence |
denotes |
DOMAIN 4: |
T884 |
3265-3280 |
Sentence |
denotes |
Flow and Timing |
T885 |
3281-3357 |
Sentence |
denotes |
Was there an appropriate interval between index test and reference standard? |
T886 |
3359-3372 |
Sentence |
denotes |
Unclear |
T887 |
3373-3426 |
Sentence |
denotes |
Did all patients receive the same reference standard? |
T888 |
3428-3437 |
Sentence |
denotes |
Yes |
T889 |
3438-3481 |
Sentence |
denotes |
Were all patients included in the analysis? |
T890 |
3483-3492 |
Sentence |
denotes |
Yes |
T891 |
3493-3553 |
Sentence |
denotes |
Could the patient flow have introduced bias? Low risk |