Id |
Subject |
Object |
Predicate |
Lexical cue |
T1697 |
0-21 |
Sentence |
denotes |
Study characteristics |
T1698 |
22-728 |
Sentence |
denotes |
Patient Sampling Purpose: to identify differences in CT imaging and clinical features between COVID‐19 and
influenza pneumonia in the early stage, and to identify the most valuable features in the differential
diagnosisDesign: diagnostic case‐control study, retrospective multicentre with historic control groupRecruitment: cases: confirmed SARS‐CoV‐2 patients; controls: influenza pneumonia patients (1 January 2015‐30 September 2019 from 2 hospitals)Sample size: n = 121 (cases = 73)Inclusion criteria: patients confirmed with SARS‐CoV‐2; controls: patients who had 9 respiratory pathogen IgM antibody tested from January 2015‐September 2019Exclusion criteria: cases: not specifiedcontrols:parainfluenza |
T1699 |
729-756 |
Sentence |
denotes |
respiratory syncytial virus |
T1700 |
757-767 |
Sentence |
denotes |
adenovirus |
T1701 |
768-782 |
Sentence |
denotes |
Legionella spp |
T1702 |
783-804 |
Sentence |
denotes |
Mycoplasma pneumoniae |
T1703 |
805-825 |
Sentence |
denotes |
Chlamydia pneumoniae |
T1704 |
826-843 |
Sentence |
denotes |
Coxiella burnetii |
T1705 |
844-864 |
Sentence |
denotes |
aspiration pneumonia |
T1706 |
865-884 |
Sentence |
denotes |
radiation pneumonia |
T1707 |
885-904 |
Sentence |
denotes |
pulmonary contusion |
T1708 |
905-921 |
Sentence |
denotes |
pulmonary oedema |
T1709 |
922-930 |
Sentence |
denotes |
neoplasm |
T1710 |
931-959 |
Sentence |
denotes |
No CT date, no clinical date |
T1711 |
960-1088 |
Sentence |
denotes |
Patient characteristics and setting Facility cases: positive RT‐PCR for 2019‐nCovFacility controls: influenza pneumoniaCountry: |
T1712 |
1089-1100 |
Sentence |
denotes |
ChinaDates: |
T1713 |
1101-1331 |
Sentence |
denotes |
1 January 2020‐15 February 2020Symptoms and severity: all patients in early stages of COVID‐19 or influenza pneumoniaDemographics: M/F: cases 41/32, controls 30/18
mean age: cases 41.9, controls 40.4Exposure history: not specified |
T1714 |
1332-1361 |
Sentence |
denotes |
Index tests Body temperature |
T1715 |
1362-1367 |
Sentence |
denotes |
Cough |
T1716 |
1368-1375 |
Sentence |
denotes |
Fatigue |
T1717 |
1376-1387 |
Sentence |
denotes |
Sore throat |
T1718 |
1388-1409 |
Sentence |
denotes |
Stuffy and runny nose |
T1719 |
1410-1476 |
Sentence |
denotes |
Target condition and reference standard(s) TC: COVID‐19 pneumonia |
T1720 |
1477-1510 |
Sentence |
denotes |
RS: RT‐PCR (sample not specified) |
T1721 |
1511-1549 |
Sentence |
denotes |
Flow and timing Time interval unclear |
T1722 |
1550-1564 |
Sentence |
denotes |
Comparative |
T1723 |
1565-1597 |
Sentence |
denotes |
Notes Overlaps with Chen X 2020 |
T1724 |
1598-1620 |
Sentence |
denotes |
Methodological quality |
T1725 |
1621-1686 |
Sentence |
denotes |
Item Authors' judgement Risk of bias Applicability concerns |
T1726 |
1687-1696 |
Sentence |
denotes |
DOMAIN 1: |
T1727 |
1697-1714 |
Sentence |
denotes |
Patient Selection |
T1728 |
1715-1771 |
Sentence |
denotes |
Was a consecutive or random sample of patients enrolled? |
T1729 |
1773-1782 |
Sentence |
denotes |
Yes |
T1730 |
1783-1817 |
Sentence |
denotes |
Was a case‐control design avoided? |
T1731 |
1819-1827 |
Sentence |
denotes |
No |
T1732 |
1828-1873 |
Sentence |
denotes |
Did the study avoid inappropriate exclusions? |
T1733 |
1875-1888 |
Sentence |
denotes |
Unclear |
T1734 |
1889-1934 |
Sentence |
denotes |
Did the study avoid inappropriate inclusions? |
T1735 |
1936-1944 |
Sentence |
denotes |
No |
T1736 |
1945-2015 |
Sentence |
denotes |
Could the selection of patients have introduced bias? High risk |
T1737 |
2016-2119 |
Sentence |
denotes |
Are there concerns that the included patients and setting do not match the review question? High |
T1738 |
2120-2129 |
Sentence |
denotes |
DOMAIN 2: |
T1739 |
2130-2152 |
Sentence |
denotes |
Index Test (All tests) |
T1740 |
2153-2252 |
Sentence |
denotes |
Were the index test results interpreted without knowledge of the results of the reference standard? |
T1741 |
2254-2267 |
Sentence |
denotes |
Unclear |
T1742 |
2268-2314 |
Sentence |
denotes |
If a threshold was used, was it pre‐specified? |
T1743 |
2316-2324 |
Sentence |
denotes |
No |
T1744 |
2325-2417 |
Sentence |
denotes |
Could the conduct or interpretation of the index test have introduced bias? High risk |
T1745 |
2418-2540 |
Sentence |
denotes |
Are there concerns that the index test, its conduct, or interpretation differ from the review question? Low concern |
T1746 |
2541-2550 |
Sentence |
denotes |
DOMAIN 3: |
T1747 |
2551-2569 |
Sentence |
denotes |
Reference Standard |
T1748 |
2570-2647 |
Sentence |
denotes |
Is the reference standards likely to correctly classify the target condition? |
T1749 |
2649-2658 |
Sentence |
denotes |
Yes |
T1750 |
2659-2759 |
Sentence |
denotes |
Were the reference standard results interpreted without knowledge of the results of the index tests? |
T1751 |
2761-2774 |
Sentence |
denotes |
Unclear |
T1752 |
2775-2878 |
Sentence |
denotes |
Could the reference standard, its conduct, or its interpretation have introduced bias? High risk |
T1753 |
2879-3001 |
Sentence |
denotes |
Are there concerns that the target condition as defined by the reference standard does not match the question? High |
T1754 |
3002-3011 |
Sentence |
denotes |
DOMAIN 4: |
T1755 |
3012-3027 |
Sentence |
denotes |
Flow and Timing |
T1756 |
3028-3104 |
Sentence |
denotes |
Was there an appropriate interval between index test and reference standard? |
T1757 |
3106-3119 |
Sentence |
denotes |
Unclear |
T1758 |
3120-3173 |
Sentence |
denotes |
Did all patients receive the same reference standard? |
T1759 |
3175-3184 |
Sentence |
denotes |
Yes |
T1760 |
3185-3228 |
Sentence |
denotes |
Were all patients included in the analysis? |
T1761 |
3230-3239 |
Sentence |
denotes |
Yes |
T1762 |
3240-3304 |
Sentence |
denotes |
Could the patient flow have introduced bias? Unclear risk |