PMC:7376974 / 41517-42447 JSONTXT 9 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T264 0-232 Sentence denotes Following an alternative strategy, a supramolecular assembly of monodisperse glycofullerenes, leading to the formation of micelles, was achieved and tested.72 These micelles present a uniform and spherical shape (Figure 6, route C).
T265 233-437 Sentence denotes The aggregation synthetic route is faster compared to a controlled synthesis of giant glycofullerenes, but it might suffer from low reproducibility and batch-to-batch differences between each formulation.
T266 438-701 Sentence denotes This self-assembled C60 functionalized with 6 or 12 mannoses exposes a large amount of carbohydrate at the surface, leading to an inhibition of Ebola virus in the nanomolar range (IC50 of 424 nM for six mannoses and 196 nM for 12 mannoses, respectively, Table 3).
T267 702-792 Sentence denotes Further in vitro studies evidenced again a good biocompatibility of these glycofullerenes.
T268 793-930 Sentence denotes While there are no in vivo studies yet, these promising results enlarge the panel of molecules in the fight against new emerging viruses.