Id |
Subject |
Object |
Predicate |
Lexical cue |
T3 |
0-168 |
Sentence |
denotes |
Since the outbreak of the novel coronavirus disease COVID-19, caused by the SARS-CoV-2 virus, it has spread rapidly worldwide and poses a great threat to public health. |
T4 |
169-275 |
Sentence |
denotes |
This is the third serious coronavirus outbreak in <20 years, following SARS in 2002–2003 and MERS in 2012. |
T5 |
276-376 |
Sentence |
denotes |
So far, there are almost no specific clinically effective drugs and vaccines available for COVID-19. |
T6 |
377-544 |
Sentence |
denotes |
Polysaccharides with good safety, immune regulation and antiviral activity have broad application prospects in anti-virus, especially in anti-coronavirus applications. |
T7 |
545-762 |
Sentence |
denotes |
Here, we reviewed the antiviral mechanisms of some polysaccharides, such as glycosaminoglycans, marine polysaccharides, traditional Chinese medicine polysaccharides, and their application progress in anti-coronavirus. |
T8 |
763-960 |
Sentence |
denotes |
In particular, the application prospects of polysaccharide-based vaccine adjuvants, nanomaterials and drug delivery systems in the fight against novel coronavirus were also analyzed and summarized. |
T9 |
961-1193 |
Sentence |
denotes |
Additionally, we speculate the possible mechanisms of polysaccharides anti-SARS-CoV-2, and propose the strategy of loading S or N protein from coronavirus onto polysaccharide capped gold nanoparticles vaccine for COVID-19 treatment. |
T10 |
1194-1297 |
Sentence |
denotes |
This review may provide a new approach for the development of COVID-19 therapeutic agents and vaccines. |