Id |
Subject |
Object |
Predicate |
Lexical cue |
T174 |
0-223 |
Sentence |
denotes |
Country (Prevalence) COHORT [Ref] Age/Sex Underlying Conditions CAPA Classification Local/Systemic Corticosteroid Use GM (ODI)/Serum BDG (pg/mL)/qPCR Species (Voriconazole Susceptibility Pattern) Treatment # Outcome |
T175 |
224-538 |
Sentence |
denotes |
Germany (5/19; 26.3%)ARDS [50] 62/F Cholecystectomy for cholecystitis, arterial hypertension, obesity with sleep apnea, hypercholesterolemia, ex-smoker, COPD (GOLD 2) Putative Inhaled steroids for COPD GM Serum negative GM BALF> 2.5 qPCR BALF = Positive Aspergillus fumigatus (S) culture from BALF VCZ Died |
T176 |
539-730 |
Sentence |
denotes |
70/M Vertebral disc prolapse left L4/5, flavectomy and nucleotomy, Ex-smoker Putative No GM Serum = 0.7 GM BALF> 2.5 qPCR BALF = Positive A. fumigatus by PCR; negative culture ISA Died |
T177 |
731-1014 |
Sentence |
denotes |
54/M Arterial hypertension, diabetes mellitus, aneurysm coiling right A. vertebralis Putative Intravenous corticosteroid therapy 0.4 mg/kg/d, total of 13 days) GM Serum negative GM BALF> 2.5 qPCR BALF = Positive A. fumigatus (S) culture from tracheal aspirate CASPO→ VCZ Alive |
T178 |
1015-1257 |
Sentence |
denotes |
73/M Arterial hypertension, bullous emphysema, smoker, COPD (GOLD 3), Previous Hepatitis B Putative Inhaled steroids for COPD GM Serum negative qPCR tracheal secretion = Positive A. fumigatus (S) culture from tracheal aspirate VCZ Died |
T179 |
1258-1378 |
Sentence |
denotes |
54/F None Putative No GM Serum = 1.3 and 2.7 qPCR tracheal secretion = Negative Negative culture CASPO→ VCZ Alive |
T180 |
1379-1668 |
Sentence |
denotes |
France (9/27; 33.3%)ARDS * [51] 53/M Hypertension, obesity, ischemic heart disease Putative Dexamethasone iv 20 mg once daily from day 1 to day 5, followed by 10 mg once daily from day 6 to day 10 GM Serum = 0.13 GM BALF = 0.89 BDG = 523 qPCR = Negative Negative culture None Alive |
T181 |
1669-1814 |
Sentence |
denotes |
59/F Hypertension, obesity, diabetes Putative No GM Serum = 0.04 GM BALF = 0.03 qPCR = Negative A. fumigatus, culture from BALF None Alive |
T182 |
1815-2062 |
Sentence |
denotes |
69/F Hypertension, obesity Putative Dexamethasone iv 20 mg once daily from day 1 to day 5, followed by 10 mg once daily from day 6 to day 10 GM Serum = 0.04 BDG = 7.8 qPCR BALF = 23.9 A. fumigatus, culture from tracheal secretion None Alive |
T183 |
2063-2301 |
Sentence |
denotes |
63/F Hypertension, diabetes, ischemic heart disease Putative Dexamethasone iv 20 mg once daily from day 1 to day 5, followed by 10 mg once daily from day 6 to day 10 GM Serum = 0.51GM BALF = 0.15 BDG = 63 Negative culture None Died |
T184 |
2302-2455 |
Sentence |
denotes |
43/M Asthma with steroid use history Putative No GM Serum = 0.04 GM BALF = 0.12 BDG = 7 qPCR = Negative A. fumigatus, culture from BALF None Alive |
T185 |
2456-2694 |
Sentence |
denotes |
79/M Hypertension Putative Dexamethasone iv 20 mg once daily from day 1 to day 5, followed by 10 mg once daily from day 6 to day 10 GM Serum = 0.02 GM BALF = 0.05 BDG = 23 qPCR BALF = 34.5 A. fumigatus, culture from BALF None Alive |
T186 |
2695-2938 |
Sentence |
denotes |
77/M Hypertension, asthma Putative Dexamethasone iv 20 mg once daily from day 1 to day 5, followed by 10 mg once daily from day 6 to day 10 GM Serum = 0.37 GM BALF = 3.91 BDG = 135 qPCR BALF = 29 A. fumigatus, culture from BALF VCZ Died |
T187 |
2939-3188 |
Sentence |
denotes |
75/F Hypertension, diabetes Putative Dexamethasone iv 20 mg once daily from day 1 to day 5, followed by 10 mg once daily from day 6 to day 10 GM Serum = 0.37 GM BALF = 0.36 BDG = 450 qPCR BALF = 31.7 A. fumigatus, culture from BALF CASPO Died |
T188 |
3189-3331 |
Sentence |
denotes |
47/M Multiple myeloma with steroid therapy Probable No GM Serum = 0.09 BDG = 14 A. fumigatus, culture from tracheal secretion None Died |
T189 |
3332-3549 |
Sentence |
denotes |
Netherlands (6/31; 19.4%)ARDS [47] 83/M Cardiomyopathy Possible Prednisolone 0ꞏ13mg/kg/day for 28 dayspre-admission GM Serum = 0.4 A. fumigatus, culture from tracheal aspirate VCZ + ANID (5/6) L-AmB (1/6) Died |
T190 |
3550-3708 |
Sentence |
denotes |
67/M COPD (GOLD 3), Post RTx NSCLC 2014 Possible Prednisolone 0ꞏ37mg/kg/day for 2 dayspre-admission NA A. fumigatus, culture from tracheal aspirate Died |
T191 |
3709-3797 |
Sentence |
denotes |
75/M COPD (GOLD 2a) Probable No GM BALF = 4.0 A. fumigatus, culture from BALF Died |
T192 |
3798-3863 |
Sentence |
denotes |
43/M None Probable No GM Serum = 0.1 GM BALF = 3.8 NA Alive |
T193 |
3864-4020 |
Sentence |
denotes |
57/M Bronchial asthma Probable Fluticasone 1ꞏ94 mcg/kg/day for 1 month pre-admission GM Serum = 0.1 GM BALF = 1.6 A. fumigatus. culture from BALF Died |
T194 |
4021-4099 |
Sentence |
denotes |
58/M None Possible No NA Aspergillus spp. (S), culture from sputum Alive |
T195 |
4100-4234 |
Sentence |
denotes |
Belgium (7/20; 35%)ARDS [52] 86/M Hypercholesterinemia NA No GM serum = 0.1 A. flavus culture from tracheal aspirate None Died |
T196 |
4235-4361 |
Sentence |
denotes |
38/M Obesity, hypercholesterinemia Proven No GM serum = 0.3 GM BALF > 2.8 A. fumigatus culture from BALF VCZ, ISA Alive |
T197 |
4362-4459 |
Sentence |
denotes |
62/M Diabetes Proven No GM serum = 0.2 GM BALF = 2 A. fumigatus culture from BALF VCZ Died |
T198 |
4460-4604 |
Sentence |
denotes |
73/M Diabetes, obesity, hypertension, hypercholesterinemia Proven No GM serum= 0.1 GM BALF > 2.8 A. fumigatus culture from BALF VCZ Alive |
T199 |
4605-4770 |
Sentence |
denotes |
77/M Diabetes, chronic kidney disease, hypertension, pemphigus foliaceus Proven Yes, ND GM serum = 0.1 GM BALF = 2.79 A. fumigatus culture from BALF VCZ Alive |
T200 |
4771-4890 |
Sentence |
denotes |
55/M HIV, hypertension, hypercholesterinemia NA No GM serum = 0.80 GM BALF = 0.69 Negative culture VCZ, ISA Died |
T201 |
4891-4986 |
Sentence |
denotes |
75/M Acute myeloid leukemia NA No GM BALF = 2.63 A. fumigatus culture from BALF VCZ Died |
T202 |
4987-5399 |
Sentence |
denotes |
France (1)ARDS [57] 74/M Myelodysplastic syndrome, CD8 + T-cell lymphocytosis, Hashimoto’s thyroiditis, hypertension, benign prostatic hypertrophy Putative No First GM on tracheal secretion = Negative First qPCR = Positive Second GM tracheal secretion = NA Second qPCR = Positive Direct smear of the second sample = branched septate hyphae A. fumigatus, culture of the second tracheal secretion None Died |
T203 |
5400-5561 |
Sentence |
denotes |
France (1/5; 20%)Mixed ICU [58] 80/M Thyroid cancer (patient presented with ARDS) Putative NA No A. flavus, culture from tracheal secretion VCZ→ ISA Died |
T204 |
5562-5780 |
Sentence |
denotes |
Italy (1)ARDS [59] 73/M Diabetes, hypertension, obesity, hyperthyroidism, atrial fibrillation Proven No GM Serum = 8.6 qPCR from paraffin block tissue = Positive A. fumigatus, culture from BALF L-AmB → ISA Died |
T205 |
5781-6161 |
Sentence |
denotes |
Austria (1)ARDS [60] 70/M COPD (GOLD 2), obstructive sleep apnea syndrome, insulin-dependent type 2 diabetes with end organ damage, arterial hypertension, coronary heart disease, and obesity Putative Inhaled Budesonide (400 mg per day) GM Serum = Negative BDG = Negative LFD Positive from endotracheal aspiration A. fumigatus, culture from endotracheal aspiration VCZ Died |
T206 |
6162-6302 |
Sentence |
denotes |
Germany (2)ARDS [61] 80/M Suspected pulmonary fibrosis ND No GM Serum = 1.5 GM BALF = 6.3 A. fumigatus, culture from BALF L-AmB Died |
T207 |
6303-6402 |
Sentence |
denotes |
70/M None ND No GM Serum = Negative GM BALF = 6.1 A. fumigatus, culture from BALF L-AmB Died |
T208 |
6403-6717 |
Sentence |
denotes |
Netherlands (1)ARDS [62] 74/F Polyarthritis, reflux, stopped smoking 20 years ago Putative No GM serum = Persistently < 0.5 GM tracheal aspirate = >3 BDG serum = 1590 A. fumigatus, culture from tracheal aspirate (R)TR34/L98HICZ = 16µg/mL, VCZ = 2µg/mL, and POSA = 0.5µg/ml VCZ + CASPO→ Oral VCZ→ L-AmB Died |
T209 |
6718-6911 |
Sentence |
denotes |
Australia (1) ARDS [63] 66/F Hypertension, osteopenia, ex-smoker (20 pack years) Putative No N/A A. fumigatus culture from tracheal aspirate (3x) VCZ + Therapeutic Drug monitoring Alive |