Id |
Subject |
Object |
Predicate |
Lexical cue |
T78 |
0-97 |
Sentence |
denotes |
Several studies from China reported high rates of Aspergillus infections among COVID-19 patients. |
T79 |
98-297 |
Sentence |
denotes |
In one study from the Jiangsu province in China, 60/257 COVID-19 (23.3%) patients had throat swab samples that tested positive for Aspergillus spp. and were reported as Aspergillus co-infections [8]. |
T80 |
298-610 |
Sentence |
denotes |
In another Chinese study from the Zhejiang province 8 of the 104 patients with COVID-19 (7.7%) patients were reported to have IPA although questions remain regarding criteria used for diagnosing IPA in this study (authors state EORTC/MSG criteria were used but all 8 patients seemingly lacked host factors) [71]. |
T81 |
611-746 |
Sentence |
denotes |
Another study from China reported that 27% of the COVID-19 patients (13/48) developed fungal infections but lacked further details [7]. |
T82 |
747-857 |
Sentence |
denotes |
In other reports from China, lower rates of fungal infections were reported ranging between 3.2–5% [54,55,72]. |
T83 |
858-978 |
Sentence |
denotes |
None of those studies have used specific definitions and standardized diagnostic algorithms to identify and define CAPA. |
T84 |
979-1179 |
Sentence |
denotes |
In fact, diagnosis of pulmonary aspergillosis is challenging with culture exhibiting limited sensitivity [73,74], and galactomannan testing—the current gold standard—is rarely available in China [75]. |
T85 |
1180-1486 |
Sentence |
denotes |
As a result, some of these reported rates are likely an underestimate of the real burden of IPA in patients with COVID-19 requiring ICU admission, while other rates may be an overestimation due to potentially misinterpreting Aspergillus colonization in the upper respiratory tract as Aspergillus infection. |