PMC:7346000 / 14892-16378 JSONTXT 11 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T78 0-97 Sentence denotes Several studies from China reported high rates of Aspergillus infections among COVID-19 patients.
T79 98-297 Sentence denotes In one study from the Jiangsu province in China, 60/257 COVID-19 (23.3%) patients had throat swab samples that tested positive for Aspergillus spp. and were reported as Aspergillus co-infections [8].
T80 298-610 Sentence denotes In another Chinese study from the Zhejiang province 8 of the 104 patients with COVID-19 (7.7%) patients were reported to have IPA although questions remain regarding criteria used for diagnosing IPA in this study (authors state EORTC/MSG criteria were used but all 8 patients seemingly lacked host factors) [71].
T81 611-746 Sentence denotes Another study from China reported that 27% of the COVID-19 patients (13/48) developed fungal infections but lacked further details [7].
T82 747-857 Sentence denotes In other reports from China, lower rates of fungal infections were reported ranging between 3.2–5% [54,55,72].
T83 858-978 Sentence denotes None of those studies have used specific definitions and standardized diagnostic algorithms to identify and define CAPA.
T84 979-1179 Sentence denotes In fact, diagnosis of pulmonary aspergillosis is challenging with culture exhibiting limited sensitivity [73,74], and galactomannan testing—the current gold standard—is rarely available in China [75].
T85 1180-1486 Sentence denotes As a result, some of these reported rates are likely an underestimate of the real burden of IPA in patients with COVID-19 requiring ICU admission, while other rates may be an overestimation due to potentially misinterpreting Aspergillus colonization in the upper respiratory tract as Aspergillus infection.