| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T176 |
0-63 |
Sentence |
denotes |
Three types of IFNs (types I, II and III) have been identified. |
| T177 |
64-114 |
Sentence |
denotes |
Type I and type II IFNs have been widely reported. |
| T178 |
115-147 |
Sentence |
denotes |
Type II IFNs only contain IFN-γ. |
| T179 |
148-307 |
Sentence |
denotes |
IFN-γ is produced by natural killer (NK) cells and activated CD4+ and CD8+ T cells in response to the cytokines such as interleukin-12 (IL-12) and IL-18 [158]. |
| T180 |
308-392 |
Sentence |
denotes |
IFN-γ binds to the type II IFN receptor composed of two subunits, IFNGR1 and IFNGR2. |
| T181 |
393-458 |
Sentence |
denotes |
IFNGR1 and IFNGR2 induce the formation of STAT1-STAT1 homodimers. |
| T182 |
459-640 |
Sentence |
denotes |
STAT1-STAT1 homodimers translocate to the nucleus and bind to the promoter of the IFN-γ-activation site (GAS) elements, to initiate the transcription of IFN-γ-regulated genes [159]. |
