| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T116 |
0-13 |
Sentence |
denotes |
7 Conclusion |
| T117 |
14-315 |
Sentence |
denotes |
In conclusion, many pharmacological agents that are widely used in clinical practice demonstrate endolysosomal pH-modulating properties both in vitro and in vivo, and should thus be considered as potential therapeutic agents for COVID-19 in light of the recent findings on the clinical efficacy of CQ. |
| T118 |
316-510 |
Sentence |
denotes |
Most of the drugs discussed in this review have good safety profiles, low cost and are widely available, which makes them interesting in the context of the rapidly advancing SARS-CoV-2 pandemic. |
| T119 |
511-727 |
Sentence |
denotes |
As some of these drugs have probably been used empirically in the treatment of COVID-19, it is hoped that colleagues worldwide will publish patient data to enable evaluation of the potential efficacy of these agents. |
| T120 |
728-977 |
Sentence |
denotes |
As effective treatment strategies for COVID-19 are still lacking, repurposing of drugs based on their lysosomotropic and endolysosomal pH-modulating effects could provide the additional preventive and therapeutic options that are desperately needed. |
