| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T193 |
0-317 |
Sentence |
denotes |
There is little doubt that oral LF can be of health benefit to the host, and while it is not considered to be absolutely necessary for mammalian life (so it is not a vitamin), it is reasonable to class it as a nutraceutical along with a variety of other molecules such as those mentioned in various papers (180, 181). |
| T194 |
318-463 |
Sentence |
denotes |
As a nutraceutical, the bioavailability of LF would clearly be an important consideration in its use for the prevention or treatment of COVID-19. |
| T195 |
464-629 |
Sentence |
denotes |
Enteric coating of LF capsules has been proposed as a measure to maximize the uptake of LF by the receptors located in the brush-border of the small intestine (182). |
| T196 |
630-890 |
Sentence |
denotes |
Enteric coating allows LF release some distance from LF-degrading pepsin activities in the stomach, allowing it to remain intact, in the form capable of binding small intestinal LF receptors for uptake and eventual transfer into the systemic circulation (182). |
| T197 |
891-1067 |
Sentence |
denotes |
In a rodent study, the “absorption” of enteric-formulated LF was approximately 10-fold higher than that of regular LF introduced into the stomach of experimental animals (128). |
| T198 |
1068-1340 |
Sentence |
denotes |
In view of these investigations, the authors of this paper regard enteric-coated LF as superior to regular LF supplements with respect to bioavailability and potential application for the prevention or therapy for coronaviruses such as the SARS-Cov-2 involved in COVID-19. |
