PMC:7271924 / 19192-20169 JSONTXT 12 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T154 0-120 Sentence denotes LF has strong antiviral activity against a broad spectrum of both naked and enveloped DNA and RNA viruses (99, 149–151).
T155 121-311 Sentence denotes LF inhibits the entry of viral particles into host cells, either by direct attachment to the viral particles or by blocking their cellular receptors (discussed in previous paragraphs) (149).
T156 312-498 Sentence denotes Some of the viruses that LF prevents from entering host cells e.g., Herpes simplex virus (162), human papillomavirus (163), human immunodeficiency virus (HIV) (164), and rotavirus (165).
T157 499-637 Sentence denotes These viruses typically utilize common molecules on the cell membrane to facilitate their invasion into cells, including HSPGs (Figure 1).
T158 638-771 Sentence denotes HSPGs provide the first anchoring sites on the host cell surface, and help the virus make primary contact with these cells (99, 162).
T159 772-870 Sentence denotes HSPGs can be either membrane bound, or in secretory vesicles and in the extracellular matrix (86).
T160 871-977 Sentence denotes It has been shown that LF is able to prevent the internalization of some viruses by binding to HSPGs (86).