PMC:7265874 / 1705-4600 JSONTXT 10 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T13 0-145 Sentence denotes Between March 12th and April 25th 2020, 34 COVID-19 patients were admitted to our ICU, of whom 20 (59%) required invasive mechanical ventilation.
T14 146-219 Sentence denotes Seven of these ventilated patients (35%) were suspected of IPA (Table 1).
T15 220-294 Sentence denotes Median age in our patient cohort was 66 (interquartile range 56–77) years.
T16 295-350 Sentence denotes Underlying comorbidities were primarily cardiovascular.
T17 351-394 Sentence denotes Only three patients were immunocompromised.
T18 395-725 Sentence denotes One patient received chronic corticosteroid treatment for pemphigus foliaceous, one patient was HIV-positive (CD4 count > 250; viral load < 20 copies, treated with antiretrovirals [lamivudine/tenofovir/nevirapine]) and one patient had been treated for acute myeloid leukaemia 8 years ago and had developed IPA during chemotherapy.
T19 726-815 Sentence denotes All patients were intubated and mechanically ventilated due to severe COVID-19 pneumonia.
T20 816-851 Sentence denotes Table 1 Patients with suspected IPA
T21 852-1179 Sentence denotes Patient ID Sex (M/F) Age Medical history Time between COVID-19 symptoms and ICU admission (days) Time between COVID-19 symptoms and intubation (days) Time between intubation and first finding of IPA (days) First BAL galactomannan index Peak BAL galactomannan index First serum galactomannan index Peak serum galactomannan index
T22 1180-1220 Sentence denotes 1 M 86 Hyperchol 7 7 9 N/A N/A 0.10 0.10
T23 1221-1274 Sentence denotes 2 M 38 Obesity, hyperchol 9 9 6 2.40 > 2.80 0.30 0.30
T24 1275-1311 Sentence denotes 3 M 62 DM 7 7 16 0.72 2.00 0.20 0.20
T25 1312-1375 Sentence denotes 4 M 73 DM, obesity, AHT, hyperchol 9 10 5 2.65 > 2.80 0.10 0.10
T26 1376-1443 Sentence denotes 5 M 77 DM, CKD, AHT, pemphigus foliaceus 9 10 2 2.79 2.79 0.10 0.10
T27 1444-1497 Sentence denotes 6 M 55 HIV, AHT, hyperchol 8 9 13 0.69 0.69 0.18 0.80
T28 1498-1544 Sentence denotes 7 M 75 AML, IPA (2012) 3 3 8 2.63 2.63 N/A N/A
T29 1545-1700 Sentence denotes Patient ID Sex (M/F) Age Medical history First positive culture CT scan Histological examinationa IPA diagnosis AspICU algorithm Antifungal therapy Outcome
T30 1701-1781 Sentence denotes 1 M 86 Hyperchol A. flavus (ETA) No scan available N/A – – None Died, ICU day 10
T31 1782-1906 Sentence denotes 2 M 38 Obesity, hyperchol A. fumigatus (BAL) + Positive Proven Absolute Voriconazole, isavuconazole Alive on MV, ICU day 28b
T32 1907-2008 Sentence denotes 3 M 62 DM A. fumigatus (BAL) No scan available Positive Proven Absolute Voriconazole Died, ICU day 20
T33 2009-2143 Sentence denotes 4 M 73 DM, obesity, AHT, hyperchol A. fumigatus (BAL) No scan available Positive Proven Absolute Voriconazole Alive on MV, ICU day 24b
T34 2144-2284 Sentence denotes 5 M 77 DM, CKD, AHT, pemphigus foliaceus A. fumigatus (BAL) No scan available Positive Proven Absolute Voriconazole Alive on MV, ICU day 21b
T35 2285-2394 Sentence denotes 6 M 55 HIV, AHT, hyperchol Negative No scan available Negative – Voriconazole, isavuconazole Died, ICU day 27
T36 2395-2489 Sentence denotes 7 M 75 AML, IPA (2012) A. fumigatus (BAL) No scan available N/A – Voriconazole Died, ICU day 8
T37 2490-2584 Sentence denotes CKD chronic kidney disease, AML acute myeloid leukaemia, IPA invasive pulmonary aspergillosis.
T38 2585-2794 Sentence denotes N/A no sample available, Hyperchol hypercholesterolaemia, AHT arterial hypertension, DM diabetes mellitus, BAL bronchoalveolar lavage, ETA endotracheal aspirate, MV mechanical ventilation arterial hypertension
T39 2795-2871 Sentence denotes aAnatomopathological examination of tissue samples obtained via bronchoscopy
T40 2872-2895 Sentence denotes bAt the time of writing