Id |
Subject |
Object |
Predicate |
Lexical cue |
T4 |
0-151 |
Sentence |
denotes |
Covid-19 is characterized by weak symptoms in most affected patients whilst severe clinical complications, with frequent fatal issues, occur in others. |
T5 |
152-210 |
Sentence |
denotes |
Disease severity is associated with age and comorbidities. |
T6 |
211-334 |
Sentence |
denotes |
Understanding of viral infectious mechanisms, and antibody immune response, can help to better control disease progression. |
T7 |
335-554 |
Sentence |
denotes |
SARS-CoV-2 has a major impact on the Renin Angiotensin Aldosterone System (RAAS), through its binding to the membrane cellular glycoprotein, Angiotensin Converting Enzyme-2 (ACE-2), then infecting cells for replication. |
T8 |
555-736 |
Sentence |
denotes |
This report hypothesizes the possible implication of an autoimmune response, induced by generation of allo- or autoantibodies to ACE-2, or to its complexes with viral spike protein. |
T9 |
737-827 |
Sentence |
denotes |
This could contribute to some delayed severe complications occurring in affected patients. |
T10 |
828-890 |
Sentence |
denotes |
We also propose a strategy for investigating this eventuality. |