LitCovid-sentences  

PMC:7252011 / 1070-2968 JSONTXT 11 Projects

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Id Subject Object Predicate Lexical cue
T11 0-15 Sentence denotes 1 Introduction
T12 16-174 Sentence denotes Fast and extended knowledge is becoming available on the new viral disease that emerged in December 2019, causing enormous challenges at international levels.
T13 175-568 Sentence denotes The pathology of this obscure virus, named Severe Acute Respiratory Syndrome - Coronavirus-2 (SARS-CoV-2), is characterized by many patients remaining asymptomatic or with only benign symptoms, but this disease becomes life-threatening in some patients and requires hospitalization in intensive care units or resuscitation [1,2], and is often with a fatal outcome, yet to be fully established.
T14 569-787 Sentence denotes Activation of the hemostasis system has been observed in many patients with severe complications, with occurrence of disseminated intravascular coagulopathy (DIC) or pulmonary embolism (PE), and multiorgan failure [3].
T15 788-891 Sentence denotes DDimer is frequently elevated, and the disease prognosis worsens with its increasing concentration [2].
T16 892-933 Sentence denotes Sepsis can also be present in some cases.
T17 934-1052 Sentence denotes Anticoagulant therapy, especially with LMWH, can improve the disease evolution and reduce the lethality incidence [4].
T18 1053-1351 Sentence denotes In addition, many patients with severe complications face a sudden worsening, starting 7 to > 14 days after the preliminary symptoms, although the immune response is effective with the presence of IgG and/or IgMs and is expected to fight the disease by controlling its pathological evolution [5,6].
T19 1352-1482 Sentence denotes This worsening is associated with an exacerbated immunological activity, a strong inflammatory response, and a cytokine storm [7].
T20 1483-1592 Sentence denotes New therapeutic approaches rely on controlling the pro-inflammatory cytokines, mainly IL-6, IL-10, and TNF-α.
T21 1593-1803 Sentence denotes Lastly, there is a strong association of disease severity with age and presence of comorbidities, mainly hypertension, diabetes, obesity, chronic obstructive pulmonary disease and cardiovascular diseases (CVD).
T22 1804-1898 Sentence denotes However, complications can also occur in younger persons without any known risk factors [1,2].