| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T336 |
0-114 |
Sentence |
denotes |
It has been reported that host cellular microRNAs (miRNAs) are involved in the regulation of virus infection [41]. |
| T337 |
115-246 |
Sentence |
denotes |
A previous study discovered that significantly up-regulated MIR301 and down-regulated MIR183/130B were found in H1N1 patients [42]. |
| T338 |
247-436 |
Sentence |
denotes |
Consistent with these results, we found that MIR183 and MIR130A/B/301 are related to four functional units of QFPD, indicating these microRNAs may exert anti−COVID-19 activity through QFPD. |
| T339 |
437-646 |
Sentence |
denotes |
In addition, CDKs have played a role in the efficient replication of various viruses, including human HIV-1, papillomaviruses, human cytomegalovirus (HCMV), herpes simplex virus (HSV) type 1 and HSV-2 [43,44]. |
| T340 |
647-878 |
Sentence |
denotes |
In agreement with these results, we found that CDK7 was predicted to enriched in the five formulae, suggesting that QFPD may regulate replication of COVID-19 viruses via CDK7 mediated cell cycle and RNA polymerase II transcription. |
| T341 |
879-1057 |
Sentence |
denotes |
Recently, a previous study showed that LXR known to regulate cholesterol homeostasis during inflammation were differentially regulated during H1N1 influenza virus infection [45]. |
| T342 |
1058-1252 |
Sentence |
denotes |
Based on our results that LXR was associated with MSXG, SGMH, XCH, WLS targets, we speculated that QFPD can regulate metabolic and pro-inflammatory processes to counter COVID-19 virus infection. |
