LitCovid-sentences  

PMC:7247521 / 35290-37273 JSONTXT 10 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T259 0-69 Sentence denotes 3.7 ACE2 and CD147 expression across tissues and co-expression genes
T260 70-241 Sentence denotes Since 2019-nCov may enter other tissues and organs through ACE2 and CD147 binding, we firstly explored the expression and distribution of ACE2 and CD147 across 53 tissues.
T261 242-425 Sentence denotes Fig. 10 A showed that the 5 top expression tissues of ACE2 were terminal ileum, testis, visceral (omentum), left ventricle and kidney cortex, which are 3 fold change higher than lung.
T262 426-569 Sentence denotes And the 5 top expression tissues of CD147 were testis, visceral (omentum), left ventricle, aorta, atrial appendage and transformed fibroblasts.
T263 570-861 Sentence denotes Then, to further understand whether QFPD only targets pneumonia or 2019-nCov, we obtained 200 co-expression genes of ACE2, 200 co-expression genes of CD147, 470 pneumonia-associated proteins, 119 HCoV-associated host proteins, and 476 co-expression genes of ACE2 in colonic epithelial cells.
T264 862-1092 Sentence denotes Fig. 10B displayed that QFPD had some common targets with these five sets, while specific 254 targets for QFPD, indicating other mechanisms of QFPD on COVID-19 in addition to 2019-nCov, pneumonia, ACE2 and CD147 related functions.
T265 1093-1166 Sentence denotes Fig. 10 ACE2 and CD147 expression across tissues and co-expression genes.
T266 1167-1169 Sentence denotes A:
T267 1170-1228 Sentence denotes Radar plot of ACE2 and CD147 expression across 53 tissues.
T268 1229-1286 Sentence denotes The expression values were converted to base-2 logarithm.
T269 1287-1345 Sentence denotes Red triangle and square mean the top 5 expression tissues.
T270 1346-1348 Sentence denotes B:
T271 1349-1574 Sentence denotes UpSet plot of proteins among QFPD, HCoV (Host_protein), pneumonia, ACE2 co-expression genes (ACE2_database), CD147 co-expression genes (CD147_database), and ACE2 co-expression genes in colonic epithelial cells (ACE2_colonic).
T272 1575-1673 Sentence denotes The horizontal bar graph at the bottom left shows the total number of proteins for each group set.
T273 1674-1763 Sentence denotes Circles and vertical lines in the x-axis mark the corresponding data sets being compared.
T274 1764-1983 Sentence denotes The vertical bar graph at the top quantitates the number of proteins in the comparisons. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)