PMC:7243778 / 26780-27660 JSONTXT 6 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T208 0-92 Sentence denotes The difference between RBD of SARS-CoV and SARS-CoV-2 is located at the C-terminus residues.
T209 93-161 Sentence denotes This change has an important impact on the cross-reactivity of nAbs.
T210 162-242 Sentence denotes This difference was observed using bioinformatic approaches of epitope analysis.
T211 243-308 Sentence denotes The antibody epitope score of SARS-CoV-2 is higher than SARS-CoV.
T212 309-512 Sentence denotes Moreover, compared with the conserved regions, the non-conserved regions had a significantly higher antibody epitope score indicating that non-conserved regions of spike proteins are much more antigenic.
T213 513-694 Sentence denotes The non-conserved regions also showed significantly higher surface epitope accessibility scores suggesting an easier accessibility for antibody recognition of non-conserved regions.
T214 695-785 Sentence denotes The divergence of spike proteins is considered as a major change in the antibody epitopes.
T215 786-880 Sentence denotes The search for SARS-CoV-2 requires more effort than simply screening SARS-CoV antibodies [95].