LitCovid-sentences  

PMC:7195088 / 29725-31117 JSONTXT 8 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T229 0-362 Sentence denotes Methylprednisolone A subgroup of patients with severe COVID-19 might develop a cytokine storm syndrome which causes rapidly progressive pneumonia, ARDS and clinical deterioration and corticosteroids administration may halt the dysregulated cytokine release • Not available • Comparison of methylprednisolone vs. standard of care in patients with severe COVID-19.
T230 363-404 Sentence denotes Open-label RCT (NCT04244591, recruiting).
T231 405-471 Sentence denotes Primary endpoint: lower Murray lung injury score at days 7 and 14.
T232 472-554 Sentence denotes • Comparison of methylprednisolone vs. standard of care in patients with COVID-19.
T233 555-596 Sentence denotes Open-label RCT (NCT04273321, recruiting).
T234 597-653 Sentence denotes Primary endpoint: treatment failure (follow-up 14 days).
T235 654-854 Sentence denotes • Comparison of inhaled alpha interferon plus methylprednisolone plus umifenovir vs. thalidomide plus inhaled alpha interferon plus methylprednisolone plus umifenovir in patients with severe COVID-19.
T236 855-906 Sentence denotes Double-blind RCT (NCT04273581, not yet recruiting).
T237 907-974 Sentence denotes Primary endpoint: time to clinical improvement (follow-up 28 days).
T238 975-1057 Sentence denotes • Comparison of different dosages of methylprednisolone in patients with COVID-19.
T239 1058-1099 Sentence denotes Open-label RCT (NCT04263402, recruiting).
T240 1100-1181 Sentence denotes Primary endpoints: (a) disease readmission at day 7; (b) critical stage at day 7.
T241 1182-1290 Sentence denotes • Comparison of siltuximab (anti–IL-6 monoclonal antibody) vs. methylprednisolone in patients with COVID-19.
T242 1291-1340 Sentence denotes Open-label RCT (NCT04329650, not yet recruiting).
T243 1341-1392 Sentence denotes Primary endpoint: ICU admission (follow-up 29 days)