Id |
Subject |
Object |
Predicate |
Lexical cue |
T194 |
136-260 |
Sentence |
denotes |
Double-blind RCT for outpatients and healthcare workers and open-label RCT for inpatients (NCT04329923, not yet recruiting). |
T195 |
261-458 |
Sentence |
denotes |
Primary endpoints: (a) release from quarantine (outpatients, follow-up 14 days); (b) discharge (inpatients, follow-up 14 days); (c) development of COVID-19 (healthcare workers, follow-up 2 months). |
T196 |
459-545 |
Sentence |
denotes |
• Comparison of hydroxychloroquine vs. ascorbic acid in contacts of COVID-19 patients. |
T197 |
546-597 |
Sentence |
denotes |
Double-blind RCT (NCT04328961, not yet recruiting). |
T198 |
598-666 |
Sentence |
denotes |
Primary endpoint: laboratory-confirmed COVID-19 (follow-up 14 days). |
T199 |
667-803 |
Sentence |
denotes |
• Comparison of tocilizumab plus hydroxychloroquine plus azithromycin vs. tocilizumab plus hydroxychloroquine in patients with COVID-19. |
T200 |
804-853 |
Sentence |
denotes |
Open-label RCT (NCT04332094, not yet recruiting). |
T201 |
854-1081 |
Sentence |
denotes |
Primary endpoints: (a) in-hospital mortality (follow-up 2 weeks); (b) need for mechanical ventilation in the ICU (follow-up 2 weeks).• Comparison of ciclesonide plus hydroxychloroquine vs. ciclesonide in patients with COVID-19. |
T202 |
1082-1131 |
Sentence |
denotes |
Open-label RCT (NCT04330586, not yet recruiting). |
T203 |
1132-1205 |
Sentence |
denotes |
Primary endpoint: SARS-CoV-2 eradication (based on virus load) at day 14. |
T204 |
1206-1332 |
Sentence |
denotes |
• Comparison of hydroxychloroquine vs. placebo in patients with COVID-19 and under biological treatment and/or JAK inhibitors. |
T205 |
1333-1384 |
Sentence |
denotes |
Double-blind RCT (NCT04330495, not yet recruiting). |
T206 |
1385-1595 |
Sentence |
denotes |
Primary endpoints: (a) incidence rate of COVID-19 (follow-up 27 weeks); (b) prevalence of COVID-19 (follow-up 27 weeks); (c) case fatality rate (follow-up 27 weeks); (d) ICU admission rate (follow-up 27 weeks). |
T207 |
1596-1704 |
Sentence |
denotes |
• Comparison of hydroxychloroquine vs. placebo for the prevention of COVID-19 in healthcare workers at risk. |
T208 |
1705-1756 |
Sentence |
denotes |
Double-blind RCT (NCT04328467, not yet recruiting). |
T209 |
1757-1819 |
Sentence |
denotes |
Primary endpoint: prevalence of COVID-19 (follow-up 12 weeks). |
T210 |
1820-1932 |
Sentence |
denotes |
• Comparison of chemoprophylaxis with lopinavir/ritonavir vs. placebo in healthcare workers exposed to COVID-19. |
T211 |
1933-1984 |
Sentence |
denotes |
Double-blind RCT (NCT04328285, not yet recruiting). |
T212 |
1985-2002 |
Sentence |
denotes |
Primary endpoint: |
T213 |
2003-2091 |
Sentence |
denotes |
Occurrence of a symptomatic or asymptomatic SARS-CoV-2 infection (follow-up 2.5 months). |
T214 |
2092-2213 |
Sentence |
denotes |
• Comparison of hydroxychloroquine vs. placebo in symptomatic COVID-19 patients or exposed healthcare workers/households. |
T215 |
2214-2257 |
Sentence |
denotes |
Double-blind RCT (NCT04308668, recruiting). |
T216 |
2258-2405 |
Sentence |
denotes |
Primary endpoints: (a) incidence of symptomatic COVID-19 among asymptomatic participants; (b) severity rating on a 3-point ordinal scale at day 14. |
T217 |
2406-2521 |
Sentence |
denotes |
• Comparison of remdesivir vs. hydroxychloroquine vs. remdesivir plus hydroxychloroquine in patients with COVID-19. |
T218 |
2522-2580 |
Sentence |
denotes |
Open-label adaptive RCT (NCT04321616, not yet recruiting). |
T219 |
2581-2651 |
Sentence |
denotes |
Primary endpoint: all-cause in-hospital mortality (follow-up 3 weeks). |
T220 |
2652-2763 |
Sentence |
denotes |
• Comparison of lopinavir/ritonavir vs. hydroxychloroquine vs. losartan vs. placebos in patients with COVID-19. |
T221 |
2764-2825 |
Sentence |
denotes |
Double-blind, adaptive RCT (NCT04328012, not yet recruiting). |
T222 |
2826-2902 |
Sentence |
denotes |
Primary endpoint: NIAID COVID-19 Ordinal Severity Scale (follow-up 60 days). |
T223 |
2903-3061 |
Sentence |
denotes |
• Comparison of convalescent plasma plus hydroxychloroquine plus azithromycin vs. hydroxychloroquine plus azithromycin in hospitalized patients with COVID-19. |
T224 |
3062-3111 |
Sentence |
denotes |
Open-label RCT (NCT04332835, not yet recruiting). |
T225 |
3112-3291 |
Sentence |
denotes |
Primary endpoints: (a) change in virus load at days 0, 4, 7, 14 and 28; (b) change in IgM COVID-19 titers at days 0, 4, 7, 14 and 28; (c) change in IgG at days 0, 4, 7, 14 and 28. |
T226 |
3292-3461 |
Sentence |
denotes |
• Comparison of lopinavir/ritonavir vs. hydroxychloroquine vs. lopinavir/ritonavir plus interferon beta-1a vs. remdesivir vs. standard of care in patients with COVID-19. |
T227 |
3462-3515 |
Sentence |
denotes |
Double-blind, adaptive RCT (NCT04315948, recruiting). |
T228 |
3516-3587 |
Sentence |
denotes |
Primary endpoint: severity rating on a 7-point ordinal scale at day 15. |