PMC:7195088 / 218-1809 JSONTXT 7 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T3 0-10 Sentence denotes Background
T4 11-207 Sentence denotes Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19), which has rapidly become epidemic in Italy and other European countries.
T5 208-316 Sentence denotes The disease spectrum ranges from asymptomatic/mildly symptomatic presentations to acute respiratory failure.
T6 317-513 Sentence denotes At the present time the absolute number of severe cases requiring ventilator support is reaching or even surpassing the intensive care unit bed capacity in the most affected regions and countries.
T7 515-525 Sentence denotes Objectives
T8 526-729 Sentence denotes To narratively summarize the available literature on the management of COVID-19 in order to combine current evidence and frontline opinions and to provide balanced answers to pressing clinical questions.
T9 731-738 Sentence denotes Sources
T10 739-802 Sentence denotes Inductive PubMed search for publications relevant to the topic.
T11 804-811 Sentence denotes Content
T12 812-1005 Sentence denotes The available literature and the authors' frontline-based opinion are summarized in brief narrative answers to selected clinical questions, with a conclusive statement provided for each answer.
T13 1007-1019 Sentence denotes Implications
T14 1020-1132 Sentence denotes Many off-label antiviral and anti-inflammatory drugs are currently being administered to patients with COVID-19.
T15 1133-1405 Sentence denotes Physicians must be aware that, as they are not supported by high-level evidence, these treatments may often be ethically justifiable only in those worsening patients unlikely to improve only with supportive care, and who cannot be enrolled onto randomized clinical trials.
T16 1406-1591 Sentence denotes Access to well-designed randomized controlled trials should be expanded as much as possible because it is the most secure way to change for the better our approach to COVID-19 patients.