Id |
Subject |
Object |
Predicate |
Lexical cue |
T34 |
0-160 |
Sentence |
denotes |
A study was attempted to narrow the existing molecular-level knowledge gap of SARS-CoV-2 by mapping the interactions between SARS-CoV-2 and human proteins [15]. |
T35 |
161-287 |
Sentence |
denotes |
With the help of affinity purification mass spectrometry (AP-MS), 332 protein–protein interactions (PPIs) could be identified. |
T36 |
288-453 |
Sentence |
denotes |
Further, 66 druggable human proteins/factors targeted by 69 medicines which were either FDA-approved or in clinical trials or pre-clinical molecules were recognized. |
T37 |
454-634 |
Sentence |
denotes |
To our interest, it was found that human proteins regulated by the mTORC1 signalling pathway, specifically LARP1 and FKBP7, interact with important viral proteins, N and Orf8 [15]. |
T38 |
635-802 |
Sentence |
denotes |
Since metformin inhibits mTOR signalling, it could act as an indirect modulator of the protein–protein complex, thus preventing the viral replication and pathogenesis. |