| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T10 |
120-330 |
Sentence |
denotes |
Thus, the unique pattern of immune dysregulation in severe COVID-19 is characterized by IL-6-mediated low HLA-DR expression and lymphopenia, associated with sustained cytokine production and hyper-inflammation. |
| T11 |
332-350 |
Sentence |
denotes |
Graphical Abstract |
| T12 |
352-362 |
Sentence |
denotes |
Highlights |
| T13 |
363-453 |
Sentence |
denotes |
• Severe COVID-19 patients display immune dysregulation or macrophage activation syndrome |
| T14 |
454-547 |
Sentence |
denotes |
• Severe respiratory failure is associated with a major decrease of HLA-DR on CD14 monocytes |
| T15 |
548-621 |
Sentence |
denotes |
• CD4 cell and NK cell cytopenias are characteristics of severe COVID-19 |
| T16 |
622-710 |
Sentence |
denotes |
• IL-6 blocker Tocilizumab partially rescues SARS-CoV-2-associated immune dysregulation |
