PMC:7143804 / 55691-56371 JSONTXT 5 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T500 0-55 Sentence denotes Figure 1 Schematic representation of the MDA reaction.
T501 56-94 Sentence denotes In panel (a), a dsDNA strand is shown.
T502 95-139 Sentence denotes In panel (b), denaturation happens at 95 °C.
T503 140-255 Sentence denotes In panel (c), the random hexamer-primers (purple) and ϕ29 DNA polymerase (blue arrow) bind to the initiation sites.
T504 256-372 Sentence denotes In panel (d), the amplification is performed by the polymerase, which binds complementary bases to the ssDNA strand.
T505 373-493 Sentence denotes In panel (e), the polymerase encounters another hexamer binded to an initiation site and starts lifting up this hexamer.
T506 494-625 Sentence denotes In panel (f), a hexamer binds to the displaced ssDNA strands and the polymerase starts the amplification from this initiation site.
T507 626-680 Sentence denotes For clarity, the amplified DNA is bordered with black.