| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T266 |
0-13 |
Sentence |
denotes |
5 Conclusion |
| T267 |
14-286 |
Sentence |
denotes |
In conclusion, we constructed the recombinant strain, rH120-S1/YZ, which was based on the backbone of the H120 vaccine strain, and replaced the S1 gene with that of the QX-like nephropathogenic strain, ck/CH/IBYZ/2011, isolated from China using the reverse genetic system. |
| T268 |
287-492 |
Sentence |
denotes |
The safety results showed that this recombinant strain was not lethal to one-day-old chicks and it had not gained the ability to tissue invasion or replication in the kidneys and lungs of infected animals. |
| T269 |
493-604 |
Sentence |
denotes |
Moreover, the viral load of the chickens was significantly decreased compared with the rH120 and rIBYZ strains. |
| T270 |
605-749 |
Sentence |
denotes |
Furthermore, rH120-S1/YZ was found to provide effective protection against challenge with the QX-like nephropathogenic strain in young chickens. |
| T271 |
750-875 |
Sentence |
denotes |
The level of antibody production in the serum of the vaccinated chickens detected by ELISA continued to increase after 7 dpi. |
| T272 |
876-1017 |
Sentence |
denotes |
Thus, rH120-S1/YZ may be considered a potential live vaccine candidate for protection against Chinese QX-like nephropathogenic IBV infection. |
