PMC:7103735 / 47258-50162 JSONTXT 9 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T396 0-42 Sentence denotes Concluding remarks and future perspectives
T397 43-206 Sentence denotes The outbreak of SARS-CoV-2 provides an unprecedented opportunity for us to keep track of a zoonotic CoV that has just crossed the species barrier to infect humans.
T398 207-410 Sentence denotes Whether the transmission of SARS-CoV-2 within humans will come to a dead end depends primarily on whether the virus has acquired the ability to transmit from person-to-person efficiently and sustainably.
T399 411-651 Sentence denotes In the cases of MERS-CoV and SARS-CoV, secondary and tertiary spreading becomes weakened, giving the opportunity for quarantine and other measures of human intervention to take effect so that human-to-human transmission cannot be sustained.
T400 652-857 Sentence denotes However, if transmissibility of SARS-CoV-2 is comparable to that of the other four community-acquired HCoVs and influenza viruses, we should prepare well for the arrival of another community-acquired HCoV.
T401 858-969 Sentence denotes In this regard, it is crucial to determine the infection rate in the epicentre of Wuhan by RT–PCR and serology.
T402 970-1143 Sentence denotes The real ratios of asymptomatic carriers and patients with mild symptoms as well as the transmission rates in secondary, tertiary, and quaternary spreading are also pivotal.
T403 1144-1276 Sentence denotes If the attack rate is sufficiently high, it will be tremendously challenging to contain the spreading before herd immunity develops.
T404 1277-1390 Sentence denotes The virulence and pathogenicity of SARS-CoV-2 seem to lie between those of SARS-CoV and community-acquired HCoVs.
T405 1391-1618 Sentence denotes If SARS-CoV-2 becomes more attenuated as it adapts well in humans and increases its person-to-person transmissibility as anticipated, similar strategies for prevention and control of CoVs and influenza viruses might be adopted.
T406 1619-1703 Sentence denotes To reduce morbidity and mortality caused by SARS-CoV-2, vaccines could be developed.
T407 1704-1855 Sentence denotes If quarantine cannot contain the spreading and if it is necessary, vaccination will provide the second opportunity to eradicate SARS-CoV-2 from humans.
T408 1856-1953 Sentence denotes The interplay between SARS-CoV-2 and host antiviral defence is at the core of viral pathogenesis.
T409 1954-2061 Sentence denotes It also determines the infection outcome and might explain the existence and risk of asymptomatic carriers.
T410 2062-2117 Sentence denotes SARS-CoV-2 is very similar to SARS-CoV in many aspects.
T411 2118-2270 Sentence denotes Lessons from other human pathogenic viruses including SARS-CoV, community-acquired HCoVs, influenza viruses, and HIVs are very enlightening and helpful.
T412 2271-2387 Sentence denotes However, SARS-CoV-2 is also a novel human pathogen that may interact with host antiviral defence in a unique manner.
T413 2388-2523 Sentence denotes Basic research in the field of SARS-CoV-2-host interaction holds the key to many important questions in disease control and prevention.
T414 2524-2685 Sentence denotes Many important questions concerning the identity and mechanisms of interferon antagonists encoded by SARS-CoV-2 will be answered in the months and years to come.
T415 2686-2806 Sentence denotes Particularly, comparative analyses of SARS-CoV-2 and SARS-CoV will advance the understanding of SARS-CoV-2 pathogenesis.
T416 2807-2904 Sentence denotes The new knowledge gained will guide the development of vaccines and anti-SARS-CoV-2 therapeutics.