Id |
Subject |
Object |
Predicate |
Lexical cue |
T396 |
0-42 |
Sentence |
denotes |
Concluding remarks and future perspectives |
T397 |
43-206 |
Sentence |
denotes |
The outbreak of SARS-CoV-2 provides an unprecedented opportunity for us to keep track of a zoonotic CoV that has just crossed the species barrier to infect humans. |
T398 |
207-410 |
Sentence |
denotes |
Whether the transmission of SARS-CoV-2 within humans will come to a dead end depends primarily on whether the virus has acquired the ability to transmit from person-to-person efficiently and sustainably. |
T399 |
411-651 |
Sentence |
denotes |
In the cases of MERS-CoV and SARS-CoV, secondary and tertiary spreading becomes weakened, giving the opportunity for quarantine and other measures of human intervention to take effect so that human-to-human transmission cannot be sustained. |
T400 |
652-857 |
Sentence |
denotes |
However, if transmissibility of SARS-CoV-2 is comparable to that of the other four community-acquired HCoVs and influenza viruses, we should prepare well for the arrival of another community-acquired HCoV. |
T401 |
858-969 |
Sentence |
denotes |
In this regard, it is crucial to determine the infection rate in the epicentre of Wuhan by RT–PCR and serology. |
T402 |
970-1143 |
Sentence |
denotes |
The real ratios of asymptomatic carriers and patients with mild symptoms as well as the transmission rates in secondary, tertiary, and quaternary spreading are also pivotal. |
T403 |
1144-1276 |
Sentence |
denotes |
If the attack rate is sufficiently high, it will be tremendously challenging to contain the spreading before herd immunity develops. |
T404 |
1277-1390 |
Sentence |
denotes |
The virulence and pathogenicity of SARS-CoV-2 seem to lie between those of SARS-CoV and community-acquired HCoVs. |
T405 |
1391-1618 |
Sentence |
denotes |
If SARS-CoV-2 becomes more attenuated as it adapts well in humans and increases its person-to-person transmissibility as anticipated, similar strategies for prevention and control of CoVs and influenza viruses might be adopted. |
T406 |
1619-1703 |
Sentence |
denotes |
To reduce morbidity and mortality caused by SARS-CoV-2, vaccines could be developed. |
T407 |
1704-1855 |
Sentence |
denotes |
If quarantine cannot contain the spreading and if it is necessary, vaccination will provide the second opportunity to eradicate SARS-CoV-2 from humans. |
T408 |
1856-1953 |
Sentence |
denotes |
The interplay between SARS-CoV-2 and host antiviral defence is at the core of viral pathogenesis. |
T409 |
1954-2061 |
Sentence |
denotes |
It also determines the infection outcome and might explain the existence and risk of asymptomatic carriers. |
T410 |
2062-2117 |
Sentence |
denotes |
SARS-CoV-2 is very similar to SARS-CoV in many aspects. |
T411 |
2118-2270 |
Sentence |
denotes |
Lessons from other human pathogenic viruses including SARS-CoV, community-acquired HCoVs, influenza viruses, and HIVs are very enlightening and helpful. |
T412 |
2271-2387 |
Sentence |
denotes |
However, SARS-CoV-2 is also a novel human pathogen that may interact with host antiviral defence in a unique manner. |
T413 |
2388-2523 |
Sentence |
denotes |
Basic research in the field of SARS-CoV-2-host interaction holds the key to many important questions in disease control and prevention. |
T414 |
2524-2685 |
Sentence |
denotes |
Many important questions concerning the identity and mechanisms of interferon antagonists encoded by SARS-CoV-2 will be answered in the months and years to come. |
T415 |
2686-2806 |
Sentence |
denotes |
Particularly, comparative analyses of SARS-CoV-2 and SARS-CoV will advance the understanding of SARS-CoV-2 pathogenesis. |
T416 |
2807-2904 |
Sentence |
denotes |
The new knowledge gained will guide the development of vaccines and anti-SARS-CoV-2 therapeutics. |