| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T53 |
0-73 |
Sentence |
denotes |
Homology analysis of the spike proteins of SARS-CoVs and related Bat-CoVs |
| T54 |
74-193 |
Sentence |
denotes |
Phylogenetic analysis of the spike protein sequences of SARS-CoV-2 and Bat-CoVs, SARS-CoV is shown in Figure 1(Fig. 1). |
| T55 |
194-481 |
Sentence |
denotes |
The results are in agreement with recent reports of an independent introduction of SARS-CoV-2 from a Bat-CoV, different from the spillover which led to the introduction of SARS-CoV, being the Bat-CoV of Rhinolophus affinis the probable ancestor of this new virus (Wong et al., 2020[18]). |
| T56 |
482-598 |
Sentence |
denotes |
Indeed, the sequences of the whole spike of this Bat-CoV and of SARS-CoV-2 share 97.7 % identity (Figure 1(Fig. 1)). |
| T57 |
599-733 |
Sentence |
denotes |
More divergence is found however in the S1 subunit, particularly in the Receptor Binding Domain (RBD) of the different spike proteins. |
| T58 |
734-939 |
Sentence |
denotes |
SARS-CoV and Bat-CoV from Rhinolophus sinicus (originally signaled as the most closely related virus to SARS-CoV-2) exhibit several amino acid substitutions and deletions in the RBD compared to SARS-CoV-2. |
| T59 |
940-1107 |
Sentence |
denotes |
The RBD of Bat-CoV from Rhinolophus affinis, although more closely related to the one of SAS-CoV-2, also displayed several amino acid substitutions (Figure 2(Fig. 2)). |
